2023
DOI: 10.3390/pharmaceutics15061583
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Exploring the Potential of Nanotechnology in Pediatric Healthcare: Advances, Challenges, and Future Directions

Abstract: The utilization of nanotechnology has brought about notable advancements in the field of pediatric medicine, providing novel approaches for drug delivery, disease diagnosis, and tissue engineering. Nanotechnology involves the manipulation of materials at the nanoscale, resulting in improved drug effectiveness and decreased toxicity. Numerous nanosystems, including nanoparticles, nanocapsules, and nanotubes, have been explored for their therapeutic potential in addressing pediatric diseases such as HIV, leukemi… Show more

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Cited by 13 publications
(3 citation statements)
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References 192 publications
(367 reference statements)
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“…Additionally, innovative approaches such as image-guided drainage and fibrinolytic therapy have revolutionized the management of conditions like parapneumonic effusion, offering high success rates and minimizing the need for invasive surgery. 5 The ambit of pediatric interventional radiology in treating children with malignancies continues to expand, encompassing procedures ranging from image-guided biopsies for diagnostic tissue procurement to advanced direct tumor therapies. Additionally, they are instrumental in placing vascular access devices like PICCs, tunneled lines, and port catheters for oncology treatments.…”
Section: Interventional Radiologymentioning
confidence: 99%
“…Additionally, innovative approaches such as image-guided drainage and fibrinolytic therapy have revolutionized the management of conditions like parapneumonic effusion, offering high success rates and minimizing the need for invasive surgery. 5 The ambit of pediatric interventional radiology in treating children with malignancies continues to expand, encompassing procedures ranging from image-guided biopsies for diagnostic tissue procurement to advanced direct tumor therapies. Additionally, they are instrumental in placing vascular access devices like PICCs, tunneled lines, and port catheters for oncology treatments.…”
Section: Interventional Radiologymentioning
confidence: 99%
“…These challenges and risks can be categorized as follows. Health and environmental concerns [ [207] , [208] , [209] , [210] , [211] , [212] , [213] , [214] , [215] ], coming from releasing nanomaterials, which have unique properties, into the environment can pose human and ecological risks (such as toxicity and bioaccumulation) and potential harm to ecosystems. Researchers and policymakers should collaborate to develop guidelines for the safe use and disposal of nanomaterials, ensuring minimal environmental impact.…”
Section: Challenges and Risks Associated With The Use Of Nanotechnolo...mentioning
confidence: 99%
“…Nanocarriers, capable of penetrating deeper skin layers, enhance the bioavailability and efficacy of active compounds. This integration has led to substantial advancements, ranging from understanding nanoparticle penetration mechanisms to exploring experimental models and therapeutic applications in dermatology [38][39][40]. Nanotechnological strides are evident in non-invasive vaccination strategies and the facilitation of transdermal drug delivery, which are reshaping contemporary skincare practices [41,42].…”
Section: Introductionmentioning
confidence: 99%