2018
DOI: 10.31744/einstein_journal/2018rb4587
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Abstract: The biology of stem cells is one of the most dynamic and promising fields of the biological sciences, since it is the basis for the development of organisms. Its biological complexity demands efforts from several lines of research aimed mainly at its therapeutic use. Nanotechnology has been emerging as a new field of study, which shows great potential in the treatment of various diseases. This new area of health has been called “Nanomedicine” or “Bionanotechnology”, which can be applied in Medicine by transpor… Show more

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Cited by 5 publications
(3 citation statements)
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“…Schwann cells, fibroblasts and macrophages also play important roles in regulating the regeneration microenvironment and improving the regeneration effect through a variety of manual interventions ( Qian et al, 2019 ). Therefore, in peripheral nerves, stem/progenitor cells present potentials in the treatment, cure, and repair of damaged tissues secondary to injury and inflammation ( Mazzeo and Santos, 2018 ). In such a context of inflammation and nerve injury, the sciatic nerve is especially exposed because of its very special anatomical feature: it is the largest peripheral nerve in the human body, but also the most exposed to forces of torsion, traction and pressure during daily activities ( Sladjana et al, 2008 ).…”
Section: Discussionmentioning
confidence: 99%
“…Schwann cells, fibroblasts and macrophages also play important roles in regulating the regeneration microenvironment and improving the regeneration effect through a variety of manual interventions ( Qian et al, 2019 ). Therefore, in peripheral nerves, stem/progenitor cells present potentials in the treatment, cure, and repair of damaged tissues secondary to injury and inflammation ( Mazzeo and Santos, 2018 ). In such a context of inflammation and nerve injury, the sciatic nerve is especially exposed because of its very special anatomical feature: it is the largest peripheral nerve in the human body, but also the most exposed to forces of torsion, traction and pressure during daily activities ( Sladjana et al, 2008 ).…”
Section: Discussionmentioning
confidence: 99%
“…With the continuous advancement in nanotechnology, combining stem cells and exosomes with nanotechnology makes treatment more precise and effective. Nanotechnology can allow stem cells to be targeted to specific locations and can also help stem cells in applying their therapeutic potential to treat, heal, and repair damaged tissues in an effective and safe manner 210,211 . Nanotechnology can solve the abnormal proliferation and differentiation of stem cells during the treatment process, 212 improves the possibility of reducing the limitations of stem cells in the treatment of cell regeneration in injured or degenerated organs, enhances tissue repair, and assists in cellular reconstruction.…”
Section: Novel Nanoformulations Loaded With Stem Cells and Exosomesmentioning
confidence: 99%
“…[5][6][7] Nanotechnology is the synthesis of functional structures on nanoscale, which results in materials with new chemical, biological and physical characteristics as well as novel conductivity, reactivity, functional conformation and smart structures. 8,9 These smart structures provide proper responses, including anti-oxidative, adhesive, migrating and proliferative ones, to physiochemical stimuli in cells in a particular, controlled way. 10 Nanotechnology helps stem cells utilize their therapeutic potential for the treatment and repair of damaged tissues.…”
Section: Introductionmentioning
confidence: 99%