Nanotechnologies for early diagnosis, in situ disease monitoring, and prevention

Wu, Tong; Chiu, Hsiao-Yu; Yu, John; Cautela, Mafalda P.; Sarmento, Bruno; Neves, José das; Catala, Carme; Pazos-Pérez, Nicolás; Guerrini, Luca; Alvarez-Puebla, Ramón A.; Vranješ-Đurić, Sanja; Ignjatović, Nenad; Uskoković,; Uskoković, Dragan

doi:10.1016/b978-0-323-48063-5.00001-0

Cited by 18 publications

(16 citation statements)

References 357 publications

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“…The incomplete arrival of the direction away from its objective tissue or organ will now cause healthy tissue toxicity as well as the conveying of dosages in a sub-therapeutic level at the objective component. Their ability to move various organic restrictions inside the casing, for instance, the bloodbrain barrier commits any error has extraordinary outcomes, evenly at the environment, for example, the expanding call for radionuclides, also nano fibres with carbon likewise are implicated to consume the ozone layer in the biological system [21,[108][109][110].…”

Section: Current Limitation and Safety Of Nanoparticlesmentioning

confidence: 99%

Application of some nanoparticles in the field of veterinary medicine

Youssef

El-Banna

El-Zorba

et al. 2019

International Journal of Veterinary Science and Medicine

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Nanotechnology is a fast-growing technology that plays an important great impact on various fields of therapeutic applications. It is capable for solving several problems related to animal health and production. There are different nano-systems such as liposomes, metallic nanoparticles, polymeric micelles, polymeric nanospheres, functionalized fullerenes, carbon nanotubes, dendrimers, polymer-coated nanocrystals and nanoshells. In this review, we mentioned different methods for the preparation and characterization of nanoparticles. This review is concerned mainly on nanoparticle systems for antibiotic delivery which suffer from poor bioavailability and many side effects. Nanoparticles are characterized by many features include their minimal size, colossal surface zone to mass extent. The development of antimicrobials in nanoparticle systems is considered an excellent alternative delivery system for antimicrobials for the treatment of microbial diseases by increasing therapeutic effect and overcoming the side effects. In this paper, we reviewed some antimicrobial nanoparticle preparations and we focused on florfenicol and neomycin nanoparticle preparations as well as chitosan and silver nanoparticles preparations to prepare, characterize and compare their different pharmacological effects.

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Section: Current Limitation and Safety Of Nanoparticlesmentioning

confidence: 99%

Application of some nanoparticles in the field of veterinary medicine

Youssef

El-Banna

El-Zorba

et al. 2019

International Journal of Veterinary Science and Medicine

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“…11 mm), which in combination with targeting mechanism majorly restrict irradiation mostly to malignant tissues. In addition to that, 90 Y has a physical half-life suitable for the radiotherapy (64.1 h) and 94% of radiation is delivered within 11 days after the drug admission [251].…”

Section: Introductionmentioning

confidence: 99%

Current outlook on radionuclide delivery systems: from design consideration to translation into clinics

et al. 2019

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Radiopharmaceuticals have proven to be effective agents, since they can be successfully applied for both diagnostics and therapy. Effective application of relevant radionuclides in pre-clinical and clinical studies depends on the choice of a sufficient delivery platform. Herein, we provide a comprehensive review on the most relevant aspects in radionuclide delivery using the most employed carrier systems, including, (i) monoclonal antibodies and their fragments, (ii) organic and (iii) inorganic nanoparticles, and (iv) microspheres. This review offers an extensive analysis of radionuclide delivery systems, the approaches of their modification and radiolabeling strategies with the further prospects of their implementation in multimodal imaging and disease curing. Finally, the comparative outlook on the carriers and radionuclide choice, as well as on the targeting efficiency of the developed systems is discussed.

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“…It was shown that after intravenous administration, HAp/Ch particles accumulated in the spleen and the liver, while HAp/Ch-PLGA particles accumulated in the lungs. 20 A new procedure for radiolabelling nano--HAp with 125 I was developed to determine the biodistribution and accumulation of the composite particles in different organs. Thus, the created nano-objects are highly prospective as carriers of medicaments to organs where their accumulation was detected.…”

Section: Nano-bio Materials For Preventive and Regenerative Medicinementioning

confidence: 99%

“…It also provides the information important for the understanding of the biomolecule/nanosystems interface and the environmental fate of nanomaterials used in medicine. The book includes a chapter by Vranješ-Đurić and Ignjatović,20 in which hybrids between radionuclides and nanoparticles are discussed from the viewpoints of their structure, fabrication, fate in the body and applications in imaging and targeted radiotherapy. The final chapter 30 by Uskoković and Uskoković took on the risky task of challenging some of the unequivocally accepted prospects in the field of medical nanotechnologies and questioning its paradigms and premises that rarely get questioned, if at all.…”

Section: Nano-bio Materials For Preventive and Regenerative Medicinementioning

confidence: 99%

From molecules to nanoparticles to functional materials

Ignjatović

Marković

Jugović

et al. 2020

JSCS

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Functional nanomaterials have held a steady position at the frontier of materials science and engineering in the 21st century. "Molecular Designing of Nanoparticles with Controlled Morphological and Physicochemical Characteristics and Functional Materials Based on Them? was the title of the research project funded by the Ministry of Education, Science and Technological Development of the Republic of Serbia and performed between 2011 and 2019 in the interdisciplinary area of nanoscience and nanotechnologies. Research activities within this program were divided to five interrelated topics: (1) From molecules to nanoparticles; (2) Advanced ceramics with improved functional properties; (3) Electrode materials for lithium-ion batteries; (4) Nano-calcium phosphate in preventive and regenerative medicine; (5) Biodegradable micro- and nano-particles for the controlled delivery of medicaments. This report gives an insight into this bibliographically most impactful Serbian national project on nanotechnologies executed within the aforementioned nine-year cycle, 2011 - 2019, focusing here only on the results achieved in the past three years. The project provided an outstanding and internationally recognized contribution to synthesis, characterization and functional design of a number of materials systems, including pure and lanthanide-doped hydroxyapatite, zinc oxides, sodium cobaltates, lithium iron pyrophosphates, lithium iron silicates and a number of polymeric systems. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. III45004: Molecular designing of nanoparticles with controlled morphological and physicochemical characteristics and functional materials based on them]

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Nanotechnologies for early diagnosis, in situ disease monitoring, and prevention

Cited by 18 publications

References 357 publications

Application of some nanoparticles in the field of veterinary medicine

Application of some nanoparticles in the field of veterinary medicine

Current outlook on radionuclide delivery systems: from design consideration to translation into clinics

From molecules to nanoparticles to functional materials

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