Nanostructured luminescently labeled nucleic acids

Abstract

Important and emerging trends at the interface of luminescence, nucleic acids and nanotechnology are: (i) the conventional luminescence labeling of nucleic acid nanostructures (e.g. DNA tetrahedron); (ii) the labeling of bulk nucleic acids (e.g. single-stranded DNA, double-stranded DNA) with nanostructured luminescent labels (e.g. copper nanoclusters); and (iii) the labeling of nucleic acid nanostructures (e.g. origami DNA) with nanostructured luminescent labels (e.g. silver nanoclusters). This review surveys recent advances in these three different approaches to the generation of nanostructured luminescently labeled nucleic acids, and includes both direct and indirect labeling methods.

Recent advances in fluorescence sensors based on DNA–MOF hybrids

“…Lipid, peptide and DNA are all attractive surface ligands for MOFs . Among these, due to DNA designable sequence and precise base‐pairing properties, DNA has been a superstar molecule in the field of nanomaterials …”

One‐step synthesis of cationic gold nanoclusters with high catalytic activity on luminol chemiluminescence reaction

“…In addition, metal NCs can be stabilized with ligands such as DNA, proteins, polymers. [ 27–31 ] The peroxidase‐like activity of bovine serum albumin (BSA)–Au NCs was first reported by Wang's group. [ 32 ] Subsequently, Chen's group found that the BSA–Au NCs could enhance the CL emission of the luminol–H 2 O 2 reaction.…”

Electrochemiluminescent functional nucleic acids‐based sensors for food analysis

“…The overall number of publications involving ECL has increased year‐by‐year . A great deal of ECL luminophores and the detailed ECL mechanisms have been extensively studied by many researchers, and well summarized in several reviews . Therefore, in this review, ECL substrates and their related luminescent mechanisms are not presented in detailed.…”

“…[31,32] A great deal of ECL luminophores and the detailed ECL mechanisms have been extensively studied by many researchers, [11,15,21,[33][34][35][36][37][38] and well summarized in several reviews. [7,31,32,[39][40][41][42] Therefore, in this review, ECL substrates and their related luminescent mechanisms are not presented in detailed.…”