Nanosized hydroxyapatite synthesized by precipitation in a gelatin solution

Фомин, А. С.; Баринов, С. М.; Иевлев, В. М.; Фадеева, И. В.; Komlev, V. S.; Belonogov, E. K.; Turaeva, T. L.

doi:10.1134/s0012500806110073

Cited by 13 publications

(10 citation statements)

References 12 publications

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“…40 ± 44 Figure 1 shows the specific surface of powders as a function of the gelatine concentration; the synthesis was carried out through the precipitation from calcium nitrate and ammonium hydrogenphosphate solutions. 43 The maximum specific surface was *220 m 2 g 71 (which corresponded to the crystal size <15 nm). This was con- firmed by a direct study using transmission electron microscopy (TEM) (Fig.…”

Section: Nanocrystalline Hydroxyapatite and Ceramics On Its Basismentioning

confidence: 96%

Calcium phosphate-based ceramic and composite materials for medicine

Баринов¹

2010

Russ. Chem. Rev.

142

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Section: Nanocrystalline Hydroxyapatite and Ceramics On Its Basismentioning

confidence: 96%

Calcium phosphate-based ceramic and composite materials for medicine

Баринов¹

2010

Russ. Chem. Rev.

142

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“…Particle size and the formation of agglomerates in PVP-HA composites are affected by PVP content, as shown in [68]. HA formation in the PVP solution according to reaction (1) takes place in the following manner: ions of calcium interact with phosphate ions, resulting in the formation of amorphous calcium phosphate, and each of its molecule is surrounded by PVP chains [69]. The highly sensitive method of electron microdiffraction shows that these composites (sample 1, Table 1) include a calcium phosphate phase.…”

Section: Dimensional Analysismentioning

confidence: 99%

Composite Polyvinylpyrrolidone–Sodium Alginate—Hydroxyapatite Hydrogel Films for Bone Repair and Wound Dressings Applications

et al. 2021

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Today, the synthesis of biocompatible and bioresorbable composite materials such as “polymer matrix-mineral constituent,” which stimulate the natural growth of living tissues and the restoration of damaged parts of the body, is one of the challenging problems in regenerative medicine. In this study, composite films of bioresorbable polymers of polyvinylpyrrolidone (PVP) and sodium alginate (SA) with hydroxyapatite (HA) were obtained. HA was introduced by two different methods. In one of them, it was synthesized in situ in a solution of polymer mixture, and in another one, it was added ex situ. Phase composition, microstructure, swelling properties and biocompatibility of films were investigated. The crosslinked composite PVP-SA-HA films exhibit hydrogel swelling characteristics, increasing three times in mass after immersion in a saline solution. It was found that composite PVP-SA-HA hydrogel films containing HA synthesized in situ exhibited acute cytotoxicity, associated with the presence of HA synthesis reaction byproducts—ammonia and ammonium nitrate. On the other hand, the films with HA added ex situ promoted the viability of dental pulp stem cells compared to the films containing only a polymer PVP-SA blend. The developed composite hydrogel films are recommended for such applications, such as membranes in osteoplastic surgery and wound dressing.

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“…According to Andrei et al [1], the red-shift of the peaks in amide I and amide II bands for the "bulk" HA/collagen samples as the HA/collagen weight ratio increases indicates a certain degree of interaction between the HA nanoparticles and collagen. Typical peaks of phosphate bands also appeared, such as v 1 960 cm 1 , v 3 1044 cm 1 and 561 cm 1 [34][35][36]. CO 3 2 v 3 bands at 1450, 1420 cm 1 and CO 3 2 v 2 band at 873 cm 1 in the spectrum of the hollow spherical Sr-HA indicate CO 2 is probably incorporated into the solution from the air during the mineralization [34].…”

Section: Characterizationmentioning

confidence: 99%

Biomimetic synthesis of calcium-strontium apatite hollow nanospheres

Gan

Han

et al. 2010

Sci. China Chem.

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In this work, calcium-strontium apatite (Sr-HA) hollow nanospheres were synthesized by a facile biomimetic method. The structure and property of Sr-HA were characterized by FESEM, TEM, HRTEM, XRD and FT-IR spectroscopy. The influences of different ratios of calcium and strontium on the morphologies of the Sr-HA products were investigated. The experimental results revealed that the hollow spherical Sr-HA, with a size of 30-120 nm in diameter, could be synthesized when the molar ratio of Ca/Sr was 1:1. The possible formation mechanism of the hollow Sr-HA was proposed. The drug release experiments indicated that the hollow spherical Sr-HA had the property of sustained release. calcium-strontium apatite, hollow nanosphere, biomimetic synthesis

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Nanosized hydroxyapatite synthesized by precipitation in a gelatin solution

Cited by 13 publications

References 12 publications

Calcium phosphate-based ceramic and composite materials for medicine

Calcium phosphate-based ceramic and composite materials for medicine

Composite Polyvinylpyrrolidone–Sodium Alginate—Hydroxyapatite Hydrogel Films for Bone Repair and Wound Dressings Applications

Biomimetic synthesis of calcium-strontium apatite hollow nanospheres

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