Nanosilver: Potent antimicrobial agent and its biosynthesis

Sarsar, Vikas; Selwal, Krishan K.; Selwal, Manjit K.

doi:10.5897/ajb2013.13147

Cited by 27 publications

(5 citation statements)

References 38 publications

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“…Silver nanoparticles (AgNPs) are widely known for their antimicrobial, anti-cancerous, and anti-inflammatory effect ( Sharma et al, 2020 ). The small size, high surface area, and dispersion rate are the main features that offer an antimicrobial effect with a long-lasting impact ( Khan et al, 2020 ) and the penetration ability to microbial cells ( Vikas et al, 2014 ). Synthesis of nanoparticles can be categorized into physical, chemical, and biological methods.…”

Section: Introductionmentioning

confidence: 99%

Biosynthesis of silver nanoparticles with antibacterial, antioxidant, anti-inflammatory properties and their burn wound healing efficacy

2022

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The current study aims to develop a novel burn wound ointment consisting of sheep’s tail ointment loaded with AgNP. The AgNP in the ointment serves as an antibacterial, antioxidant and anti-inflammatory agent. The AgNP was developed via the biological method with the assistance of the medicinal plant Rhodiola rosea. The characterization of AgNP was assessed using UV-Vis spectroscopy, FTIR, Zeta Potential, XRD, PCCS, SEM, and EDX techniques. The formation of AgNP was confirmed by UV-Vis spectrum at the absorbance of ∼430 nm, and the biomolecules responsible for reducing and capping the AgNP were characterized by FTIR analysis. The stability of AgNP was determined with Zeta potential, which revealed a highly stable colloidal solution with a surface charge of −68.38 ± 3.4 mV. The synthesized AgNP had a face-centered cubic structure with a crystallite size of 23 nm and average grain size of 67.5 nm. The SEM image showed a fairly monodisperse 20 nm-sized spherical-shaped AgNP. The synthesized AgNP contained high purity of the silver, and a low concentration of AgNP inhibited both Gram-positive and Gram-negative bacteria. Moreover, the scavenging activity of AgNP was investigated using DPPH and H2O2 scavenging assay, and the results revealed a dose-dependent antioxidant activity with the highest activity at a concentration of 450 μg/ml. Finally, the burn wound healing effect was evaluated by applying the AgNP-loaded ointment to the wound site of BALB/c mice. The in-vivo studies confirmed that AgNP-loaded ointment reduced the wound size, decreased the epidermis layer, and lowered mast cell migration compared to untreated burn wounds. And the synthesized AgNP regulated both pro-inflammatory and anti-inflammatory gene expression, thereby promoting burn wound closure on BALB/c mice. The developed AgNP-loaded ointment has the potential to be applied in the biomedical field.

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Section: Introductionmentioning

confidence: 99%

Biosynthesis of silver nanoparticles with antibacterial, antioxidant, anti-inflammatory properties and their burn wound healing efficacy

2022

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“…Moreover, the large specific surface area of the nanomaterial makes it highly active compared to its macro-and microparticle format. For example, AgNP and nano-ZnO, which are commonly used in nanoenabled food packaging, have greater activity for antimicrobial performance than particles of larger dimensions [35,36].…”

Section: Nanomaterialsmentioning

confidence: 99%

Nanomaterial in Food Packaging: A Comprehensive Review

Barage

Lakkakula

Sharma

et al. 2022

Journal of Nanomaterials

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Food packaging industry is going through various scientific evolutions as per the preferences of the consumers along with the consumer trends. Current trends focus on not only protecting the food intelligently but also making it visually appealing to the consumer. In recent years, considerable attention is been given to replace nonbiodegradable materials with ecofriendly biodegradable composite material. Nanotechnology is flourishing and has proven to be a great incorporation to the packaging industry, as it can also overcome the drawbacks of the existing methods. Various nanomaterials have been explored and tested for manufacturing of packaging materials. In the present review, we discussed on current trends in food packaging and their drawbacks with respect to over consumption of plastic and how sustainable packaging is being implemented. Furthermore, nanotechnology is becoming a promising and widely used potential in food packaging industry along with nanomaterials currently being used such as zinc nanoparticles, polymer clay nanoparticles, and silver nanoparticles in food packaging. This information will broaden our current understanding on potential and problems associated with nanotechnology in food packaging.

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“…The extracts of the microorganisms at a time can behave as both the capping agents as well as reducing agent. The preparation of silver nanoparticles by using polysaccharides along with water as the capping agent is recognized as polysaccharide technique [14]. The nanoparticles of silver can also be synthesized by using numerous irradiation methods like UV-irradiation, microwave, gamma rays and through sonochemical methods [15].…”

Section: Synthesis Of Silver Nanoparticlesmentioning

confidence: 99%

Synthesis, Characterization and Antimicrobial Properties of Silver Nanocomposites

Abbas¹,

Naeem²,

Iftikhar³

et al. 2018

Silver Nanoparticles - Fabrication, Characterization and Applications

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Nanoparticles and polymers in their respective fields have contributed greatly in the form of science and hence in daily life application products. But due to lack in emerging technologies for developing silver nanocomposites with polymers and other materials, the nanoparticle-based products have conquered little less attention. Hereby, an effort is made to put a light on already developed functional materials containing silver nanoparticles and also to look forward their scope in daily life applications. A little more insight into antimicrobial properties of such materials will also be elaborated. Finally, the optimal amounts of silver that cannot be health hazardous to living being especially human and overall environmental impacts of Nanocomposites are presented.

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Nanosilver: Potent antimicrobial agent and its biosynthesis

Cited by 27 publications

References 38 publications

Biosynthesis of silver nanoparticles with antibacterial, antioxidant, anti-inflammatory properties and their burn wound healing efficacy

Biosynthesis of silver nanoparticles with antibacterial, antioxidant, anti-inflammatory properties and their burn wound healing efficacy

Nanomaterial in Food Packaging: A Comprehensive Review

Synthesis, Characterization and Antimicrobial Properties of Silver Nanocomposites

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