Nanoscaled interdigitated electrode arrays for biochemical sensors

Gerwen, P. Van; Laureyn, Wim; Laureys, Wim; Huyberechts, G.; Beeck, Maaike Op de; Baert, Kris; Suls, Johannes; Sansen, Willy; Jacobs, P; Hermans, L.; Mertens, R.

doi:10.1016/s0925-4005(98)00128-2

Cited by 358 publications

(153 citation statements)

References 6 publications

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“…These are dependent on the electrode material and the electrolyte solution [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15], but for horizontal electrode surfaces they can be approximated by…”

Section: Equivalent Circuit Modelmentioning

confidence: 99%

“…These electrode arrays have become more prominent as a sensor device due to the ongoing miniaturization of electrodes and the low cost of these systems [5]. An important advantage of these sensors is its simple and inexpensive mass-fabrication process and the ability to use them over a wide range of applications without significant changes in the sensor design [6][7]. Another potential benefit is the ability to integrate electrodes with instrumentation to develop autonomous, lab-on-chip measurement systems.…”

Section: Introductionmentioning

confidence: 99%

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Geometric parameters optimization of planar interdigitated electrodes for bioimpedance spectroscopy

Ibrahim

Claudel

Kourtiche

et al. 2013

Journal of Electrical Bioimpedance

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This paper is concerned with a physical model of an interdigitated sensor working in a frequency range from 100 Hz to 10 MHz. A theoretical approach is proposed to optimize the use of the sensor for bioimpedance spectroscopy. The correlation between design parameters and frequency behavior in coplanar impedance sensors are described. CoventorWare  software was used to model the biological medium loaded interdigital sensor in three dimensions to measure its electrical impedance. Complete system simulation by a finite element method (FEM) was used for sensor sensitivity optimization. The influence of geometrical parameters (number of fingers, width of the electrodes) on the impedance spectroscopy of the biological medium was studied. The simulation results are in agreement with the theoretical equations of optimization. Thus, it is possible to design a priori such sensor by taking into account the biological medium of interest that will load the sensor.

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Section: Equivalent Circuit Modelmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Geometric parameters optimization of planar interdigitated electrodes for bioimpedance spectroscopy

Ibrahim

Claudel

Kourtiche

et al. 2013

Journal of Electrical Bioimpedance

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“…In recent years, microfabricated interdigitated array (IDA) microelectrodes have received great attention in the areas of impedimetric immunosensing and biosensing (Van Gerwen et al, 1998;Laureyn et al, 1999aLaureyn et al, ,b, 2000, and impedance measurement for studies of biological cell behaviors (Ehret et al, 1997(Ehret et al, , 1998). …”

Section: Interdigitated Array Microelectrodes (Idas) In Impedance Meamentioning

confidence: 99%

“…Several studies have shown that IDA microelectrodes have great promises in the field of label-free impedimetric biosensing (Laureyn et al, 1999a,b;Van Gerwen et al, 1998). The IDA microelectrodes are capable of monitoring the changes of the electrical properties in the immediate neighborhood of their surfaces.…”

Section: Electrochemical Impedance Biosensors Using Redox Probesmentioning

confidence: 99%

“…It is reported that 95% of the current between the two finger electrodes in an IDA flows above the electrode surface within a distance that equals the sum of electrode width and space (Fig. 7A) (Van Gerwen et al, 1998). Therefore, the size of the IDA electrode must be chosen for different biological entities in consideration of their sizes (could be nanometer to micrometer) to achieve a sensitive biosensor for that type of biological entity.…”

Section: Electrochemical Impedance Biosensors Using Redox Probesmentioning

confidence: 99%

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Food‐borne Pathogenic Bacteria

Shi

Xie

Zhou

2017

Food Safety in China

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The realization of rapid, sensitive, and specific methods to detect foodborne pathogenic bacteria is central to implementing effective practice to ensure food safety and security. As a principle of transduction, the impedance technique has been applied in the field of microbiology as a means to detect and/or quantify foodborne pathogenic bacteria. The integration of impedance with biological recognition technology for detection of bacteria has led to the development of impedance biosensors that are finding wide-spread use in the recent years. This paper reviews the progress and applications of impedance microbiology for foodborne pathogenic bacteria detection, particularly the new aspects that have been added to this subject in the past few years, including the use of interdigitated microelectrodes, the development of chip-based impedance microbiology, and the use of equivalent circuits for analysis of the impedance systems. This paper also reviews the significant developments of impedance biosensors for bacteria detection in the past 5 years, focusing on microfabricated microelectrodes-based and microfluidic-based Faradaic electrochemical impedance biosensors, non-Faradaic impedance biosensors, and the integration of impedance biosensors with other techniques such as dielectrophoresis and electropermeabilization. Published by Elsevier Inc.

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