Nanoparticle analysis for various medicinal drugs and human body saliva at macromolecular level

Abstract

The spectral bio-diagnosis of normal human body saliva sample shows the following functional compounds and it is related to various proteins and enzymes. Because of the presence of water in the saliva sample, the hydroxyl group is observed in the form of O-H at 3,305 cm -1 , because of the presence of lipids, the functional group C-H is obtained from 2,928 to 2,856 cm -1 , due to the presence of amide-I in the form of C=N and C=C obtained at 1,658 cm -1 , the proteins are exhibited. Due to the presence of aliphatic CH 2 , the Lipids, Adenine, Cytosine, Collagen are observed at 1,455 cm -1 , because of the presence of Carbohydrates, Phospholipids, Nucleic acids, the functional groups C=O and P=O from 1,159 to 1,064 cm -1 are exhibited. Due to the presence of Phenylalanine, Tyrosine, Cystine and Hydroxyapatite C-C twist, C-C stretch, C-S stretch and PO 4 2-are observed at 748 and 483 cm -1 . Silver nanoparticle has attracted considerable interest due to their extensive applicability in various areas such as electronics, catalysis, chemistry, energy and medicine. To study the opto-electronics properties of the samples, it was mixed with silver nanoparticles and characterized.

Anti-Bacterial and Anti-Candidal Activity of Silver Nanoparticles Biosynthesized Using Citrobacter spp. MS5 Culture Supernatant

“…The FTIR spectrum showed major intense absorbance peaks at 3732 cm −1 , 3602 cm −1 , 3455 cm −1 , 3015 cm −1 , 2968 cm −1 , 2249 cm −1 , 2143 cm −1 , 1994 cm −1 , 1949 cm −1 , 1739 cm −1 , 1637 cm −1 , 1522 cm −1 , 1437 cm −1 , 1366 cm −1 , 1217 cm −1 , 1026 cm −1 , 898 cm −1 and 762 cm −1 ( Figure 6 ). In this FTIR spectrum, some peaks located in the range of 3000–3600 cm −1 may be due to the presence of O-H and N-H groups with AgNPs [ 31 , 32 ]. The band located at 2249 cm −1 and 1739 cm −1 due to vibration of C-N and C=O groups respectively [ 33 ].…”

Optical and Photoacoustic Properties of Laser-Ablated Silver Nanoparticles in a Carbon Dots Solution

“…The photoacoustic signals that were registered in the presence of Ag–NPs/CD have the information about the amplitude of pressure fluctuations ( ). Hence, can be calculated using RG formula as follows: where , , and are the setup constant which should be obtained by calibrating the setup, and they are functions of chopper frequenc ( ) [ 47 ]. Hence, aluminium foil 0.0017 cm was used to obtain the setup constant.…”

“…Figure 14 shows the photoacoustic setup [ 38 , 47 ] for the measurement of the thermal effusivity of CD and Ag–NPs/CD. The setup works based on the interaction of a He–Ne laser with sample and generation of phonon.…”

Methods in Raman spectroscopy for saliva studies – a review

“…[69] In conjunction with developments in portable, easy-to-use lab-on-a-chip devices, this might serve as a catalyst for decentralized medicine and a move away from a single disease diagnosis to a more all-encompassing concept of "health surveillance" and monitoring. [130,287]…”