Nanoceria as antioxidant: Synthesis and biomedical applications

Abstract

The therapeutic application of nanomaterials has been a focus of numerous studies in the past decade. Due to its unique redox properties, cerium oxide (ceria) is finding widespread use in the treatment of medical disorders caused by the reactive oxygen intermediates (ROI). The radicalscavenging role of ceria nanoparticles (nanoceria) have been established, as well as the autocatalytic ability of nanoceria to regenerate under various environmental conditions. The synthesis of nanoceria in biocompatible media has also been reported along with cell viability in order to determine the potential use of nanoceria in biomedical applications.

Efficacy of nanoceria for periodontal tissues alteration in glutamate-induced obese rats—multidisciplinary considerations for personalized dentistry and prevention

“…Potential biomedical applications of nanocrystalline cerium dioxide has been widely studied [28][29][30][31][32][33][34]. Nanoceria was proved to be able to participate in biological processes as a regulator of reactive oxygen species and free radicals acceptor [28]; and its efficacy for number of biomedical applications namely age-related male infertility [31], gastrointestinal motility with potential for prokinetic treatment and prevention in elderly [32], and efficacy for prophylaxis of erosive and stressinduced ulcerative lesions in the gastric mucosa of rats [33].…”

“…Nanocrystalline cerium dioxide (ceria nanoparticles nanoceria, NCD, nCeO2) is well-known as antioxidant potentially effective for various biological applications [28][29][30][31][32][33][34].…”

Nanoceria and Its Perspective in Cancer Treatment

“…[21]. In order to get the desired effect or application synthesis of nanoceria in a biocompatible way is a must and that is a pretty challenging task [27]. were used as oxidizing agent and pH adjustment.…”

Synthesis and Characterization of Various Metal Ions Doped CeO2 Nanoparticles Derived from the Azadirachta Indica Leaf Extracts

“…Rare earth oxides nanoparticles are used in biomedical applications like radical scavenging of antioxidants 14,15 . The biomedical properties of metal oxide nanoparticles have been studied in recent years.…”

“…The biomedical properties of metal oxide nanoparticles have been studied in recent years. Among the rare-earth oxides CeO 2 NPs are widely used for biological applications have mostly involved the consumption of mammalian cells [9][10][11] . However, the CeO 2 NPs are effectively used in cancer treatment 12 and inflammation 13 …”