2021
DOI: 10.1111/dth.15100
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Nails and COVID ‐19 – A comprehensive review of clinical findings and treatment

Abstract: The SARS‐CoV‐2 infection, responsible for COVID‐19, has raised the interest for infection‐associated muco‐cutaneous symptoms. While dermatologic symptoms in general gained an increasing awareness, affection of the nail organ has been mentioned only recently. We provide a narrative review on COVID‐19 manifestation on the nail organ and add symptoms induced by personal protective measures and SARS‐CoV‐2 vaccination. Available treatment options are discussed.

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Cited by 14 publications
(16 citation statements)
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“…Nails, as for hair, can reflect the state of health of the patient in recent months, as the nails of the hands grow on average about 2 mm per month [64]. Cases are emerging in which, after infection with SARS-CoV-2, certain changes have been observed in the fingernails and toenails, which are popularly known as "COVID-19 nails" [66]. Although, dermatologically speaking, one could not speak of COVID-19 nails as such, but rather that there are manifestations in the nails because of COVID-19.…”
Section: Nailsmentioning
confidence: 99%
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“…Nails, as for hair, can reflect the state of health of the patient in recent months, as the nails of the hands grow on average about 2 mm per month [64]. Cases are emerging in which, after infection with SARS-CoV-2, certain changes have been observed in the fingernails and toenails, which are popularly known as "COVID-19 nails" [66]. Although, dermatologically speaking, one could not speak of COVID-19 nails as such, but rather that there are manifestations in the nails because of COVID-19.…”
Section: Nailsmentioning
confidence: 99%
“…These are horizontal spots and indentations on the surface of the nails that manifest themselves a month or two months after SARS-CoV-2 infection [56]. These lesions appear as small grooves and the longer the involvement lasts, the wider the band becomes, albeit these alterations in the nails can also be triggered later after any important infectious process or in any disease besides COVID-19 [66,67]. In this sense, Beau's lines can appear, in addition to COVID-19 [68], in diseases such as pneumonia or hand, foot, and mouth disease, and are due to the fact that the body is wise and prefers to focus all its functionality on the vital organs, rather than in the secondary ones, such as the nails [64].…”
Section: Nailsmentioning
confidence: 99%
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“…In addition to nail changes, other changes of the nail apparatus such as periungual desquamation, pernio-like periungual erythematous edema (COVID-toe or finger), and acral gangrene have been described in patients with COVID-19 [ 15 ].…”
Section: Introductionmentioning
confidence: 99%
“…Como foram recentemente reconhecidas, ainda não se estabeleceu as manifestações ungueais mais comuns e o perfil de pacientes mais acometidos, sendo perceptível o número extremamente limitado de publicações a respeito nas principais bases de dados internacionais. (Zhao et al, 2020;Wollina et al, 2021) Os sintomas ungueais da COVID-19 representam uma dentre as várias lacunas na compreensão desta infecção emergente. A importância desses sintomas ainda é desconhecida devido à escassez de trabalhos científicos, o que pode prejudicar a avaliação completa dos pacientes com COVID-19 (Singh et al, 2021)…”
Section: Introductionunclassified