Onychomadesis in a COVID-19 patient

Ivanova, Zlatina; Aleksiev, Teodor; Dobrev, Hristo

doi:10.1007/s10354-022-00988-1

Cited by 3 publications

(6 citation statements)

References 19 publications

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“…Nevertheless, as far as we know, the chance is relatively low in ordinary situations. Unless apparent systemic, infectious, or neoplastic nail disorders or direct trauma are found, a surgeon can consider some circumstances affecting the microcirculation of the fingertip, which lead to nail plate disorders [5,[8][9][10]. Recently, some reports showed that nail change is related to coronavirus disease 2019; however, there were no infections, especially viral, in this case [8].…”

Section: Discussionmentioning

confidence: 73%

Nail growth disorder in multiple fingers following harvesting of radial forearm free flap for phalloplasty in gender-affirming surgery: a case report

Jung,

Jeong,

Kim

2024

Arch Hand Microsurg

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Nail growth disturbance commonly takes place after trauma or relevant diseases, such as infections and tumors. However, abnormal growth of the nail plate sometimes occurs without an obvious causative factor. This report presents the case of a patient who underwent male genital reconstruction with a radial forearm free flap for gender affirmation. Although the entire process was smooth, with no accidental events, the second, third, and fourth phalangeal nail plates of the hand from which the flap was harvested showed no evident growth of the fingernail 2 months postoperatively. Nail production was preserved in the remaining fingernails. Typical symptoms, such as redness, swelling, and tenderness, were noted upon clinical observation. Eventually, nail production restarted 5 months after surgery. Steroid and antibiotic treatment was attempted to reduce periungual inflammation. Additionally, close observation with psychological support was conducted.

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Section: Discussionmentioning

confidence: 73%

Nail growth disorder in multiple fingers following harvesting of radial forearm free flap for phalloplasty in gender-affirming surgery: a case report

Jung,

Jeong,

Kim

2024

Arch Hand Microsurg

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“…These are rare changes that occur in patients of all ages, regardless of their origin [104,105]. As a result of infection with the SARS-CoV-2 virus, the following have been reported: the following changes on the nails: a red crescent sign, Mees' lines, Beau's lines [106][107][108]. The red crescent sign is the most common post-COVID-19 change that affects the nails.…”

Section: Nail Changesmentioning

confidence: 99%

“…A raised erythematous line over the distal end of the lunula is described [ 104 , 108 ]. This symptom usually occurs 2–3 weeks after the SARS-CoV infection and disappears spontaneously within 2–3 months [ 106 , 108 , 109 ]. The red crescent symptom was also reported two days after the onset of symptoms of the SARS-CoV-2 infection [ 107 ].…”

Section: Introductionmentioning

confidence: 99%

“…The red crescent symptom was also reported two days after the onset of symptoms of the SARS-CoV-2 infection [ 107 ]. Most likely, this symptom occurs as a result of an immune reaction resulting from COVID-19 directed at the capillaries of the nail bed [ 105 , 106 , 109 ]. One study conducted on 55 patients indicated that the red crescent symptom occurred in 32.5% of patients (fingernails) and in 2.3% of patients (toe nails) [ 104 ].…”

Section: Introductionmentioning

confidence: 99%

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The most common skin symptoms in young adults and adults related to SARS-CoV-2 virus infection

Zaborska,

Chruszcz,

Sadowski

et al. 2024

Arch Dermatol Res

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Scientists from various areas of the world indicate in their studies that skin lesions occur in the course of infection with the SARS-CoV-2 virus. This article is a review of the most frequently described cutaneous manifestations of SARS-CoV-2 virus infection and the potential pathophysiology of their development, as well as information on abnormalities in histopathological tests. The article describes the impact of some factors related to the COVID-19 pandemic on the exacerbation of chronic dermatological diseases. This work was constructed on the basis of 142 research studies, reviews, and meta-analyses, focusing on the methods and materials used in individual works as well as the results and conclusions resulting from them. Some skin lesions may be a potential prognostic marker of the course of the disease and may also be a prodromal symptom or the only symptom of SARS-CoV-2 virus infection. Stress related to the COVID-19 pandemic may exacerbate some chronic dermatological diseases. A correlation was observed between the type of skin lesions and the patient’s age. The occurrence of skin diseases may also be influenced by drugs used to treat infections caused by SARS-CoV-2. A relationship was observed between the patient’s ethnic origin and skin lesions occurring in the course of COVID-19. There is a need to further diagnose the cutaneous manifestations of SARS-CoV-2 infection and to learn the detailed pathomechanism of their occurrence in order to better understand the essence of the disease and find an appropriate treatment method.

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“…Though most cases are idiopathic, it can also occur secondary to infections like hand, foot and mouth disease (HFMD), inflammatory conditions like erythroderma and Kawasaki disease, and autoimmune conditions like Pemphigus vulgaris, alopecia areata or drug-induced cases, especially with chemotherapy agents, antiepileptics, azithromycin and retinoids 1–5. Rarely, onychomadesis can be associated with depression, zinc deficiency, cast immobilisation, COVID-19 infection and birth trauma 2 6 7. The median onset of nail shedding is approximately 40 days following HFMD.…”

Section: Descriptionmentioning

confidence: 99%