Muscle metastasis from hepatocellular carcinoma in a patient treated with TACE

Abstract

KEYWORDSMetastasis; Hepatocellular carcinoma; TACE.Abstract The authors describe a rare case of hepatocellular carcinoma that metastasized to the pectineal muscle of the right thigh. The patient had been treated with surgical procedures and with multiple sessions of transarterial chemoembolization, one of which was complicated by a right femoral artery hematoma at the catheter insertion site. It is unclear whether the muscle metastasis was caused by blood-borne spread or by tumor-cell seeding caused by the TACE procedure.Sommario Gli autori descrivono un raro caso di localizzazione mestastatica da epatocarcinoma in sede muscolare (muscolo pettineo della coscia dx); il paziente era stato sottoposto a procedure chirurgiche ed a Tace.Per tale motivo non è dimostrabile se l'insemenzamento sia legato ad una diffusione ematogena con interessamento del muscolo pettineo o sia legato ad un seeding iatrogeno secondario alla manovra terapeutica. ª

Muscular Metastasis of Hepatocellular Carcinoma: Case Report and Literature Review

“…Eight cases, including our own, provided histological details, and the majority of cases were moderately differentiated HCC (7/8 cases) ( 33 , 37 , 39 , 40 , 44 , 48 ). Only one case was well-differentiated HCC ( 36 ). To our knowledge, why men predominate HCC cases with metastasis to the skeletal muscle is unclear.…”