2005
DOI: 10.1111/j.1464-410x.2006.05902.x
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Mumps orchitis in the non‐immune postpubertal male: a resurgent threat to male fertility?

Abstract: As postpubertal mumps in males is associated with a 40% incidence of orchitis, parents should be made aware that failing to immunize their children threatens the future fertility of their sons. Young men not immunized as children should be counselled and offered urgent vaccination. Clinicians should be aware that epididymo-orchitis may be secondary to mumps infection even with no history or clinical evidence of parotitis.

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Cited by 59 publications
(27 citation statements)
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References 26 publications
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“…Complications of mumps include orchitis, oophoritis, aseptic meningitis, encephalitis, deafness and pancreatitis, and at least one of these occurs in up to 42% of patients with mumps [4]. Recently, there has been a resurgence in mumps orchitis, with epidemics being reported more frequently [5][6][7][8]. In our institution we are witnessing an alarming increase in the presentations of mumps orchitis in pubertal and postpubertal males.…”
Section: Introductionmentioning
confidence: 99%
“…Complications of mumps include orchitis, oophoritis, aseptic meningitis, encephalitis, deafness and pancreatitis, and at least one of these occurs in up to 42% of patients with mumps [4]. Recently, there has been a resurgence in mumps orchitis, with epidemics being reported more frequently [5][6][7][8]. In our institution we are witnessing an alarming increase in the presentations of mumps orchitis in pubertal and postpubertal males.…”
Section: Introductionmentioning
confidence: 99%
“…Efekat mumpsa na plodnost muškaraca se jedino može odrediti analizom sjemene tečnosti nakon smirivanja orhitisa [24]. Prema podacima iz literature spermatogeneza je ozbiljno poremećena kod polovine bolesnika jedan do tri mjeseca nakon oporavka od unilateralnog i bilateralnog orhitisa [16,24].…”
Section: Diskusijaunclassified
“…Prema podacima iz literature spermatogeneza je ozbiljno poremećena kod polovine bolesnika jedan do tri mjeseca nakon oporavka od unilateralnog i bilateralnog orhitisa [16,24]. Smatra se da je unilateralni orhitis povezan sa prolaznim promjenama spermatogeneze, ali zabrinjava pojava anti-spermatozoidnih antitijela 84 dana nakon infekcije koja, uprkos oporavku spermatogeneze, mogu ukazivati na poremećaj funkcije testisa i time potencijalno uticati na plodnost oboljelih [25].…”
Section: Diskusijaunclassified
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“…[3][4][5] Around 20-30 per cent of infected postpubertal males suffer from this complication as a result of haematogenous spread, generally 4-11 days after the onset of parotitis. 5 The viral infection then spreads to the epididymis, and in 10-30 per cent, bilateral orchitis occurs. Severe infection may result in testicular atrophy, presenting up to a year later, and infertility (if mumps orchialgia is bilateral).…”
mentioning
confidence: 99%