Multispectral detection for gas chromatography

Ragunathan, N.; Krock, Kevin A.; Klawun, Christoph; Sasaki, Tania A.; Wilkins, Charles L.

doi:10.1016/0021-9673(94)01292-m

Cited by 33 publications

(5 citation statements)

References 167 publications

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“…Design compromises sensitivity and resolution, with purging He or N2 gas to tune IR sensitivity and GC resolution. The ID and length of the cell are typically 0.3-1.0 mm and 50-100 mm, respectively, and so matches the average peak volume from GC capillaries [42]. Figure 3 represents a GC-FTIR setup with various interface types indicated.…”

Section: Development Of Gc-ftir Hyphenationmentioning

confidence: 94%

Molecular spectroscopy – Information rich detection for gas chromatography

Zavahir

Nolvachai

Marriott

2018

TrAC Trends in Analytical Chemistry

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Section: Development Of Gc-ftir Hyphenationmentioning

confidence: 94%

Molecular spectroscopy – Information rich detection for gas chromatography

Zavahir

Nolvachai

Marriott

2018

TrAC Trends in Analytical Chemistry

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“…FT-IR also can be used as a discrimination/separation device based on different absorption band attributes from different functional groups or different configurations of the components in the mixture. 7,8 Although the spectroscopic separation is not a physical separation as performed by multidimensional chromatographic separations, it can perform the same purpose as a chromatographic separation in certain analytical procedures.…”

mentioning

confidence: 99%

“…GC hyphenate with FT-IR (GC-FT-IR) has been used as a separation, detection, identification, and quantitative analysis tool for many applications. , Most applications utilize the GC as the separation device and the FT-IR as the detection and identification unit. FT-IR also can be used as a discrimination/separation device based on different absorption band attributes from different functional groups or different configurations of the components in the mixture. , Although the spectroscopic separation is not a physical separation as performed by multidimensional chromatographic separations, it can perform the same purpose as a chromatographic separation in certain analytical procedures.…”

mentioning

confidence: 99%

Separation of C₂-Naphthalenes by Gas Chromatography × Fourier Transform Infrared Spectroscopy (GC×FT-IR): Two-Dimensional Separation Approach

Wang

Edwards

2006

Anal. Chem.

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A two-dimensional separation approach involving gas chromatography (GC) and Fourier transform infrared spectroscopy (FT-IR) is used to separate C2-naphthalene isomers at or near baseline resolution. In addition to GC separation, the FT-IR also plays an important role in the separation, as well as its traditional role of detection and identification. This two-dimensional separation approach for the analysis of a C2-naphthalene isomeric mixture is a good example of separation design based on molecular difference and the characteristics of an analytical instrument. The details of this two-dimensional separation are discussed, along with the advantages and limitations of this approach. While two-(or multiple-)dimensional separations have demonstrated superior capabilities in the characterization of complex, largely unknown mixtures, the development of GCxFT-IR illustrates the applicability of this analytical approach in the separation of simpler but still challenging, mixtures. The GCxFT-IR results have extended this approach toward its application to the analysis of samples of more complicated composition.

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“…In gas chromatography, the transfer usually is made with a pressure-balancing Deans switch or fast multiport rotary valve. Analysis is enhanced by augmenting the separation with hyphenated detection and computer-based identification. , …”

mentioning

confidence: 99%

“…by augmenting the separation with hyphenated detection and computer-based identification. 4,5 Column switching typically is applied to complex separations, in which some single-component peaks (i.e., the Gaussian-like profiles of pure compounds) overlap. The amount of overlap was quantified previously by statistical-overlap theory (SOT).…”

mentioning

confidence: 99%

Statistical-Overlap Theory of Column Switching in Gas Chromatography: Applications to Flavor and Fragrance Compounds

Samuel

Davis

2002

Anal. Chem.

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First-column gas chromatograms (GCs) of hundreds of flavor and fragrance compounds, and second-column GCs of specific regions of these GCs, are predicted using thermodynamic databases in commercial software. A statistical-overlap theory of column switching with cryogenic focusing then is developed by mimicking the predicted GCs by two kinds of Monte Carlo simulations. In the first kind, a probability distribution is calculated for the number of compounds in a region of the first-column GC, based on the number of observed peaks in the region, the number of observed peaks in the second-column GC, and the retention-time distributions and breadths of single-component peaks in both GCs. In the second kind, criteria are established for the theory's application. The theory is applied to 12 regions of first-column GCs. The theory predicts the number of compounds in all of them and shows that separation rarely is complete in second-column GCs, when 10 or more compounds are transferred between columns. The theory also rationalizes the tedious search required to find good separation conditions by showing that column-switching gas chromatography with cryogenic focusing is inherently statistical. The number of peaks in the second-column GC can be greater than, less than, or equal to the number of peaks in the relevant region of the first-column GC, and the good conditions sought by researchers to substantially improve separation correspond to favorable "rolls of the dice" found only by trial and error.

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Multispectral detection for gas chromatography

Cited by 33 publications

References 167 publications

Molecular spectroscopy – Information rich detection for gas chromatography

Molecular spectroscopy – Information rich detection for gas chromatography

Separation of C₂-Naphthalenes by Gas Chromatography × Fourier Transform Infrared Spectroscopy (GC×FT-IR): Two-Dimensional Separation Approach

Statistical-Overlap Theory of Column Switching in Gas Chromatography: Applications to Flavor and Fragrance Compounds

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Multispectral detection for gas chromatography

Cited by 33 publications

References 167 publications

Molecular spectroscopy – Information rich detection for gas chromatography

Molecular spectroscopy – Information rich detection for gas chromatography

Separation of C2-Naphthalenes by Gas Chromatography × Fourier Transform Infrared Spectroscopy (GC×FT-IR): Two-Dimensional Separation Approach

Statistical-Overlap Theory of Column Switching in Gas Chromatography: Applications to Flavor and Fragrance Compounds

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Separation of C₂-Naphthalenes by Gas Chromatography × Fourier Transform Infrared Spectroscopy (GC×FT-IR): Two-Dimensional Separation Approach