Separation of C₂-Naphthalenes by Gas Chromatography × Fourier Transform Infrared Spectroscopy (GC×FT-IR):  Two-Dimensional Separation Approach

Abstract

A two-dimensional separation approach involving gas chromatography (GC) and Fourier transform infrared spectroscopy (FT-IR) is used to separate C2-naphthalene isomers at or near baseline resolution. In addition to GC separation, the FT-IR also plays an important role in the separation, as well as its traditional role of detection and identification. This two-dimensional separation approach for the analysis of a C2-naphthalene isomeric mixture is a good example of separation design based on molecular difference and the characteristics of an analytical instrument. The details of this two-dimensional separation are discussed, along with the advantages and limitations of this approach. While two-(or multiple-)dimensional separations have demonstrated superior capabilities in the characterization of complex, largely unknown mixtures, the development of GCxFT-IR illustrates the applicability of this analytical approach in the separation of simpler but still challenging, mixtures. The GCxFT-IR results have extended this approach toward its application to the analysis of samples of more complicated composition.

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