Multiple xanthogranulomas in an adult patient: clinical, dermoscopic, reflectance confocal microscopy and histopathological features

Lacarrubba, Francesco; Verzì, Anna Elisa; Barresi, Sebastiano; Micali, Giuseppe

doi:10.1136/bcr-2019-229772

Cited by 3 publications

(2 citation statements)

References 13 publications

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“…Our finding from LC‐OCT in the horizontal mode was comparable to previous studies using RCM [ 11 , 12 , 13 , 14 ]. Differently from RCM, LC‐OCT also enables the vertical mode, allowing the possibility to combine images and data from two different observation points.…”

Section: Discussionsupporting

confidence: 90%

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Line‐field confocal optical coherence tomography of xanthogranuloma: Correlation with vertical and horizontal histopathology

et al. 2021

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Line‐field confocal optical coherence tomography (LC‐OCT) is a new noninvasive technique for a real‐time, vertical, and horizontal imaging of the skin at cellular resolution. A 47‐year‐old female presented with a 6‐month history of an asymptomatic yellowish papule. LC‐OCT evaluation was able to show the diagnostic microscopic features of xanthogranuloma and showed an excellent correlation with vertical and horizontal histopathological sections by revealing enlarged dermal papillae containing multiple, bright roundish giant cells, corresponding to foamy histiocytes, and giant cells characterized by a dark center surrounded by a highly hyper‐refractile peripheral ring, corresponding to Touton cells. LC‐OCT may represent a valid, noninvasive alternative to histopathological examination in clinically atypical cases of xanthogranuloma.

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Section: Discussionsupporting

confidence: 90%

“…Our finding from LC-OCT in the horizontal mode was comparable to previous studies using RCM [11][12][13][14]…”

Section: Discussionsupporting

confidence: 90%

Line‐field confocal optical coherence tomography of xanthogranuloma: Correlation with vertical and horizontal histopathology

et al. 2021

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Dermoscopic and reflectance confocal microscopy features of eruptive xanthoma

Qiao

Wang

2020

Skin Research and Technology

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A 32-year-old man, with a body mass index(weight(kg)/(height(m) 2 ) of 25, presented with a 2-month history of asymptomatic numerous yellowish-brown papules on the trunk and extremities. The patient was otherwise healthy, without smoking and alcohol habits, and denied a history of diabetes. Dermatological examination disclosed multiple yellowish-brown papules ranging from 2-6 mm on the trunk and extensor surfaces of extremities (Figure 1A,B).Dermoscopy revealed a predominance of yellow-orange structureless areas with arboriform telangiectasias, surrounded by an

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Dermoscopy of penile sclerosing granuloma

et al. 2021

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Penile sclerosing granuloma is a foreign body reaction to the injection of material, usually for genital augmentation purposes. Patients commonly deny having had or performed these procedures on themselves, and diagnosis can be challenging. We describe the case of a 62-year-old man with a 10-year history of a growth on the penile shaft. Dermoscopic examination showed an orange background with shiny white structures, suggesting a granulomatous pathology. Guided biopsies confirmed a sclerosing lipogranuloma. The patient admitted to having self-injected motor oil. For the first time, we report the dermoscopic description of sclerosing granuloma, which will improve clinical diagnostic precision and guide biopsies. We also contribute the first description of a dermoscopic rainbow pattern in a granulomatous disorder; this could be due to a physical phenomenon called ‘dichroism’.

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Multiple xanthogranulomas in an adult patient: clinical, dermoscopic, reflectance confocal microscopy and histopathological features

Cited by 3 publications

References 13 publications

Line‐field confocal optical coherence tomography of xanthogranuloma: Correlation with vertical and horizontal histopathology

Line‐field confocal optical coherence tomography of xanthogranuloma: Correlation with vertical and horizontal histopathology

Dermoscopic and reflectance confocal microscopy features of eruptive xanthoma

Dermoscopy of penile sclerosing granuloma

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