2021
DOI: 10.1016/j.ijpharm.2021.120331
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Multiple variable effects in the customisation of fused deposition modelling 3D-printed medicines: A design of experiments (DoE) approach

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Cited by 21 publications
(17 citation statements)
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“…In pharmacy, FDM combined with HME and optimized formulation compositions have also recently shown to be an attractive option for the development of pharmaceutical tablets and implants where adjustable drug release patterns are required [56][57][58][59]. FDM coupled with passive diffusion has shown to be an accessible loading method for filaments to allow for the manufacture of tailored personalised medicines in clinical settings [60].…”
Section: Introductionmentioning
confidence: 99%
“…In pharmacy, FDM combined with HME and optimized formulation compositions have also recently shown to be an attractive option for the development of pharmaceutical tablets and implants where adjustable drug release patterns are required [56][57][58][59]. FDM coupled with passive diffusion has shown to be an accessible loading method for filaments to allow for the manufacture of tailored personalised medicines in clinical settings [60].…”
Section: Introductionmentioning
confidence: 99%
“…The most used techniques for the development of medicines are the extrusion techniques—semisolid extrusion and FDM, stereolithography, inkjet printing and selective laser sintering (SLS) [ 15 ]. Thanks to the versatility of 3D printing in the development of personalized medicines, it has been used in the production of the most diverse pharmaceutical forms, such as oral delivery devices (tablets, caplets, and printlets) [ 16 , 17 , 18 , 19 ], skin products (films, microneedles and patches) [ 20 , 21 ], implants [ 22 , 23 ], and scaffolds [ 24 , 25 ], among others.…”
Section: Introductionmentioning
confidence: 99%
“…The main polymers reported for this technique are PVA (poly(vinyl alcohol)), PLA (polylactic acid) and EVA (Ethylene Vinyl Acetate) [69]. Moreover, PCL (polycaprolactone) [70,71] and polymethacrylates, as Eudragit ® [72] are being well explored in the pharmaceutical field due to their versatility. On the Encouraged by the development of 3D printing technology, a great range of polymers are arising to achieve diverse requirements of biomedical applications [58].…”
Section: D Printing Techniquesmentioning
confidence: 99%