“…10.-The onset of symptoms in this woman, aged 36, dated back about six months before clinical attention. She complained of vague but persistent pain in the lower abdomen.…”
“…10.-The onset of symptoms in this woman, aged 36, dated back about six months before clinical attention. She complained of vague but persistent pain in the lower abdomen.…”
“…During the 12 years of this survey there were 9 such patients (13 per cent) of whom 3 were successfully treated. This tendency for patients who have been successfully treated for head and neck cancer to develop another cancer has already been noted by Epstein and Shaw (1958). These authors (Epstein et al, 1960) produced evidence which showed that this was a true increase in incidence and not merely the natural incidence of cancer in the age group involved.…”
Section: Second Primary Carcinomasmentioning
confidence: 69%
“…This tendency for patients who have been successfully treated for head and neck cancer to develop another cancer has already been noted by Epstein and Shaw (1958). These authors (Epstein et al, 1960) produced evidence which showed that this was a true increase in incidence and not merely the natural incidence of cancer in the age group involved. This vulnerability to a second primary cancer is a factor that should be considered in the management of patients who have been successfully treated for cancer in the head and neck.…”
A study of 144 patients with cancer of the head and neck showed that 67 (46 per cent) developed recurrent cancer. Radical second treatment, almost exclusively by surgery, secured an 11 out of 67 or 16 per cent crude 5-year survival rate for recurrent head and neck cancer. Further analysis showed that the prospects of successfill second treatment were negligible or nil with certain identifiable tumours or tumour sites. When these identifiable cases are excluded the survival rate for head and neck cancer became 11 out of 45 or 24 per cent. Age and general condition rendered some patients unfit for radical surgery. In this series 30 patients were treated by radical surgery with a patients cured : patients surgically treated ratio of 11 out 0x30 or 36 per cent.
“…Opinions vary greatly on these points, and widely differing conclusions based on clinical, experimental, pathological, or necropsy material have been propounded by such authors as Warren and Gates (1932), Hurt and Broders (1933), Lund (1933), Bugher (1934), Eisenstaedt (1938, Kirshbaum andShively (1938), Stalker et at. (1939), Ewing (1940), Peller (1941, Hellendall (1943), Warren and Ehrenreich (1944), Watson (1953), Epstein andShaw (1958), Fried (1958), and Dibble and Chambers (1960). A comprehensive review of these opinions is given by the last-mentioned authors.…”
Dacie, J. V. (1962). The Haemolytic Anaemias, 2nd ed., part. 2, p. 360. Churchill, London.Graham, A. F., Crawford, T. B. B., and Marrian, G. F. (1946). Biochem.7., 40, 256. Heubner, W., and Wolff, K. (1936
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