Archives of Dermatology
 1971
DOI: 10.1001/archderm.103.5.543
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Multiple keratoacanthomas

A. W. Kopf1
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Cited by 15 publications

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“…Familial KA was seen in two brothers 19 with multiple tumors affecting principally the soles of the feet. Multiple non familial KA unrestricted to the distal phalanx has been reported in three cases 7,8,12 and eruptive KA in one patient 34 …”
Section: Discussionmentioning
confidence: 99%
“…Whether trauma plays a role in DKA has not been shown conclusively. Kopf 7 reported the case of a patient who had had numerous KAs since the age of 12 years. They appeared on his fingertips at the site of punctures made to obtain blood.…”
Section: Discussionmentioning
confidence: 99%
“…In typical cases 1,5–10 the microscopic features of DKA consist of epidermal hyperkeratosis and parakeratosis associated with a central keratin‐filled crater 20 . The histologic changes of DKAs have the same general configuration as KAs elsewhere, but they tend to be more vertically oriented, have more dyskeratotic cells, fewer neutrophils and eosinophils in their epithelium, and little or no fibrosis at their bases 12 …”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Familial KA was seen in two brothers 19 with multiple tumors affecting principally the soles of the feet. Multiple non familial KA unrestricted to the distal phalanx has been reported in three cases 7,8,12 and eruptive KA in one patient 34 …”
Section: Discussionmentioning
confidence: 99%
“…Whether trauma plays a role in DKA has not been shown conclusively. Kopf 7 reported the case of a patient who had had numerous KAs since the age of 12 years. They appeared on his fingertips at the site of punctures made to obtain blood.…”
Section: Discussionmentioning
confidence: 99%
“…In typical cases 1,5–10 the microscopic features of DKA consist of epidermal hyperkeratosis and parakeratosis associated with a central keratin‐filled crater 20 . The histologic changes of DKAs have the same general configuration as KAs elsewhere, but they tend to be more vertically oriented, have more dyskeratotic cells, fewer neutrophils and eosinophils in their epithelium, and little or no fibrosis at their bases 12 …”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…But whether trauma plays a part in DKA has not been shown conclusively. Kopf 8 reported a patient who had had numerous KAs since the age of 12 years. They appeared on his fingertips at the site of punctures made to obtain blood.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…A potential mechanism for the involution of the KA after MTX treatment is the decrease in DNA synthesis in the rapidly dividing tumour (10). Certain patients, however, are unable to tolerate systemic MTX due to the adverse effects while, in others, the KAs do not respond to systemic MTX (11).…”
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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