Multiple-drug resistant Trypanosoma congolense populations in village cattle of Metekel district, north-west Ethiopia

Afewerk, Y; Clausen, Peter; Abebe, Girma; Tilahun, Getachew; Mehlitz, D

doi:10.1016/s0001-706x(00)00108-x

Cited by 86 publications

(84 citation statements)

References 11 publications

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“…These lowered PCV of parasitemic animals was previously reported in similar studies elsewhere [21,30,33,34]. The finding of aparasitemic animals with mean PCV values of ≤ 24% might be due to the inadequacy of the technique used for detection or delayed recovery of anaemic situation after recent treatment with trypannocidal drugs or factors other than trypanosomosis such as compound effects of poor nutrition and blood feeding helminth infections such as haemonchosis and bunostomosis [35,36].…”

Section: Hematological Examinationsupporting

confidence: 75%

Prevalence of Bovine Trypanosomosis in Dembecha Woreda Amhara Region, Northwest Ethiopia

Mekonnen¹,

Eshetu²,

Zeryehun³

2017

J Vet Sci Technol

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This study was conducted in Dembecha Woreda of Amhara region, Northwest Ethiopia. The study was carried out on 384 indigenous cattle kept in mixed crop-livestock production system to estimate the prevalence of bovine trypanosomosis and associated risk factors. The study employed parasitological survey (buffy coat examination) and hematological study (packed cell volume [PCV] and thin blood smear). In the present study, the overall prevalence of trypanosomosis was 8.6% (33/384). Trypanosoma congolense (54.54%) and Trypanosome vivax (45.45%) were the only two species of Trypanosomas encountered in the study area. Among the risk factors, sex and age were found to have no significant association with the prevalence of trypanosomosis (p>0.05), but body condition and coat color of animals were found to have a significant association (p<0.05) with prevalence of trypanosomosis in the studied animals. In this study infected animals were with mean PCV value of 22.94 ± 2.70% which is significantly lower (p<0.05) than that of the non-infected animals (27.24 ± 5.02%). The study concluded that Trypanosomosis being an economically important disease in cattle the 8.6% prevalence entail that more attention should be given to be adapting on integrated disease control strategy including the vector as well as the parasites.

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Section: Hematological Examinationsupporting

confidence: 75%

Prevalence of Bovine Trypanosomosis in Dembecha Woreda Amhara Region, Northwest Ethiopia

Mekonnen¹,

Eshetu²,

Zeryehun³

2017

J Vet Sci Technol

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“…Even for these, relapses and multi-drug resistant population have started to emerge [9][10][11][12][13] . Therefore, the need to source for safer, cheaper and readily available sources of medicaments cannot be over-emphasized.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Anti-trypanosomal Properties of Four Extracts of Leaves, Stem and Root Barks of <i>Prosopis africana</i> in Laboratory Animals

Atawodi¹,

Ogunbusola²

2010

Biokemistri

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Qualitative phytochemical and anti-trypanosomal properties of the petroleum ether, chloroform, methanol and aqueous extracts, obtained by cold extraction from the leaves, stem bark and roots of Prosopis africana were evaluated. The methanolic and aqueous extracts of the stem bark and leaves of the plant contained alkaloids, saponins, tannins and flavonoids. Anthraquinone was present in the stem bark methanolic extract and in the methanolic and aqueous extracts of the root as well as the aqueous extract of the leaves. Resins was present in the petroleum ether and chloroform extracts of the stem bark and leaves, while tannins was detected in the methanol and aqueous extracts of the stem bark and leaves of the plant in addition to the petroleum ether and chloroform extracts of the root bark. All the solvent extracts showed strong in vitro anti-trypanosomal activity and 2 and 4 mg/ml, but in vivo only the methanolic extract of the leaves displayed the most promising anti-trypanosomal effect at 200 mg/kg dose. Hence, Prosopis africana extracts possess significant anti-trypanosomal activity to warrant bioassay-guided evaluation and identification of the active principle.

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“…This result was comparable with works different scholars: Twelde (2001) who reports (15%) at Keto settlement area south western Ethiopia; Habtewold (1993 and at Humbo larena of Wolaita zone (9.3%) and at Konso wereda (11.5%). But, slightly lower than the finding of Afework (1998) at Pawe, North-west Ethiopia (17.2%), Abebe and Jobere (1996) for tsetse infested Muturi (1999) at Merab Abaya, south west Ethiopia (66.1%), Afework et al, (2001) at Pawe, North west Ethiopia (60.9%) and Abebe and Jobre (1996) for tsetse infested area of Ethiopia (58.5%).…”

Section: Discussionmentioning

confidence: 69%

Tsetse density and bovine trypanosomosis in selected sites of Konta, Ethiopia

Wondimu¹,

Reta²,

Fekadu³

2017

J. Vet. Med. Anim. Health

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A cross-sectional study was conducted in selected sites of Southern Nation, Nationalities and People Regional State (SNNPRS) of Konta, Ethiopia. The purposes of study were to determine the apparent density of tsetse flies and prevalence of bovine trypanosomosis. Ngu traps for entomological survey were deployed at grazing and watering points of animals in the village of Dolba (Kerara Peasants Association, PAS) and near Gojeb River. Assessment of tsetse indicated the presence of Glossina pallidipes with the apparent density 8.45% flies/trap/day. Other biting flies (tabanids) were also caught along with tsetse that transmits trypanosomes mechanically. For parasitological study, a total of 400 blood samples were collected from randomly selected animals and examined for the presence of trypanosomes and indicate overall prevalence of trypanosomosis in study cattle as 12%. The dominant trypanosome species were found Trypanosoma conglonse 29 (60.4%) followed by Trypanosoma vivax 14 (29.2%), Trypanosoma bruci 3 (6.25%) and mixed infection (T. congolonse and T. vivax) of 2 (4.2%). Based on these results it is concluded that trypanosomosis is a major constraint of livestock production in the study area.

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Multiple-drug resistant Trypanosoma congolense populations in village cattle of Metekel district, north-west Ethiopia

Cited by 86 publications

References 11 publications

Prevalence of Bovine Trypanosomosis in Dembecha Woreda Amhara Region, Northwest Ethiopia

Prevalence of Bovine Trypanosomosis in Dembecha Woreda Amhara Region, Northwest Ethiopia

Evaluation of Anti-trypanosomal Properties of Four Extracts of Leaves, Stem and Root Barks of <i>Prosopis africana</i> in Laboratory Animals

Tsetse density and bovine trypanosomosis in selected sites of Konta, Ethiopia

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