Multipass time-of-flight mass spectrometers with high resolving powers

A high-resolution multi-reflection time-of-flight mass spectrograph for precision mass measurements at RIKEN/SLOWRI

“…However, we do see a periodic fluctuation in the intensity. This periodic fluctuation is consistent with the effect of 4-fold symmetry of the optics [53] of the mirrors. We have observed that this effect can be mitigated or exacerbated by Table 3 Calculated variation in ToF caused by variation in bias potential.…”

“…In recent years, a new type of ToF-MS, the so-called Multi-Reflection Time-of-Flight Mass Spectrograph (MRTOF-MS) [18,21,19,20], has been pioneered. It is based on an electrostatic ion trap, wherein low-energy ions (with kinetic energy <5 keV/q) reflect between a pair of energy isochronous, grid-free, electrostatic mirrors to produce an extremely long flight path.…”

A novel principle for an ion mirror design in time-of-flight mass spectrometry

“…For compact TOFMS instruments with two oppositely mounted reflectrons in a multiple-ion-bounce mode a mass resolution in the range of 31,000-55,000 was achieved for biological molecules using up to 10 reflections [26]. For lighter molecules, a mass resolution of 18,000 after more than 100 reflections has been reported by Wollnik and Casares [15] and up to 50,000 after 31 reflections was achieved by Casares et al [16] and Ishida et al [17]. This approach requires pulsed reflectron voltages for the axial inlet and exit of the ions.…”

A multi-reflection time-of-flight mass separator for isobaric purification of radioactive ion beams

“…This was demonstrated by Piyadasa et al [4] in combination with a MALDI ion source and by Casares et al [5] with a threemirror arrangement where a mass resolving power of m/ m ≈ 50,000 was achieved. Further devices were constructed mainly consisting of two rotationally symmetric ion mirrors [6][7][8] or of planar mirrors [9,10].…”