Multimodal imaging of sarcoid choroidal granulomas

Modi, Yasha S.; Epstein, Aliza; Bhaleeya, Swetangi; Harbour, J. William; Albini, Thomas A.

doi:10.1186/1869-5760-3-58

Cited by 44 publications

(33 citation statements)

References 11 publications

(13 reference statements)

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“…It has also been reported as a useful tool in the management of different ocular inflammatory disorders like Vogt Koyanagi Harada's disease, [122,123] sarcoidosis, [124] birdshot chorioretinopathy, [125] and infectious choroiditis [126,127].…”

Section: Enhanced Depth Imaging Optical Coherence Tomographymentioning

confidence: 99%

A comprehensive review of diagnostic imaging technologies to evaluate the retina and the optic disk

2015

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Ophthalmic imaging has undergone a revolution over the past 20 years with increasingly efficient and high-definition modalities now available. The use of wide-field retinal angiography, fundus autofluorescence, state-of-the-art spectral domain, and enhanced depth imaging optical coherence tomography has proven to be effective in this field. This comprehensive review is devoted to retinal and optic disk imaging modalities and their clinical implications. It is based on the published literature in the field of ophthalmic imaging with a focus on recent advances. Ophthalmic imaging plays a crucial role in the management of patients with both isolated retinal disease and systemic diseases with ocular manifestations. Evolving technology enables imaging of ocular disease in vivo, facilitating objective assessment of disease progression and response to treatment. These latest technical improvements in ophthalmic imaging are now a part of standard ophthalmic assessment in academic centers and most private practices. In the coming years, further advances may improve diagnostic sensitivity and enable cost-effective screening of large populations.

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Section: Enhanced Depth Imaging Optical Coherence Tomographymentioning

confidence: 99%

A comprehensive review of diagnostic imaging technologies to evaluate the retina and the optic disk

2015

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“…[ 36 ] On SD-OCT, sarcoid granulomas generally appear as homogenous, hyporeflective, well-demarcated choroidal lesions. [ 32 37 ] The adjacent choroidal tissue may be normal,[ 37 ] or may present loss of the typical vascular pattern. [ 32 ] After initiating proper immunosuppressant treatment, such lesions reduce in diameter.…”

Section: Sarcoidosismentioning

confidence: 99%

“…[ 32 ] After initiating proper immunosuppressant treatment, such lesions reduce in diameter. [ 37 ] On early-phase and mid-phase ICG angiography, granulomas generally appear as confluent hypocianescent areas that may or may not disappear on late-phase angiography depending on their thickness. [ 31 ] Choroidal imaging could be useful in confirming the diagnosis and assessing the treatment response in ocular sarcoidosis.…”

Section: Sarcoidosismentioning

confidence: 99%

Clinical applications of choroidal imaging technologies

Chhablani

Barteselli

2015

Indian J Ophthalmol

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Choroid supplies the major blood supply to the eye, especially the outer retinal structures. Its understanding has significantly improved with the advent of advanced imaging modalities such as enhanced depth imaging technique and the newer swept source optical coherence tomography. Recent literature reports the findings of choroidal changes, quantitative as well as qualitative, in various chorioretinal disorders. This review article describes applications of choroidal imaging in the management of common diseases such as age-related macular degeneration, high myopia, central serous chorioretinopathy, chorioretinal inflammatory diseases, and tumors. This article briefly discusses future directions in choroidal imaging including angiography.

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“…2 The SD-OCT characteristics of sarcoidrelated choroidal granulomas have been previously described. [3][4][5][6] Resolution of the hyporeflective granulomas, resolution of associated subretinal fluid, and a return of normal-appearing choroidal architecture on SD-OCT after treatment with oral steroids have been reported. 3,4 The purpose of this report is to describe the SS-OCT findings in patients with choroidal granulomas in the treated, or convalescent, stage of disease.…”

mentioning

confidence: 99%