Multichannel surface plasmon resonance biosensor with wavelength division multiplexing

Dostálek, Jakub; Vaisocherová, Hana; Homola, Jiřı́

doi:10.1016/j.snb.2004.12.096

Cited by 131 publications

(61 citation statements)

References 19 publications

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“…Thus sensing channels on the SPR cell can only be arranged in one dimension and the sensor throughput is limited. Several attempts to achieve higher throughput had resulted in lower refractive index resolution [37]. It should be noted that several works reported the implementation of combined angular-spectral interrogation in SPR sensing.…”

Section: Surface Plasmon Resonance: Phase Vs Amplitudementioning

confidence: 99%

Phase‐sensitive surface plasmon resonance biosensors: methodology, instrumentation and applications

et al. 2012

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International audienceSurface Plasmon Resonance (SPR) has become a central tool for label-free characterization of biomolecular interactions. Based on monitoring of amplitude characteristics, conventional SPR sensors have been extensively explored, commercialized and applied for studies of many important interactions (antigen-antibody, protein-ligand etc), but this technology still lacks of sensitivity for the detection of relatively small and low copy number compounds. Phase-sensitive SPR has recently emerged as an upgrade of this technology to resolve the sensitivity issue. Profiting from a sharp phase jump under SPR and ultra-sensitive tools of its control, this technology offers up to 100-time improvement of the detection limit, giving access to the detection of trace amounts of small molecular weight analytes (drugs etc). This paper intends to provide a tutorial on basic concepts of phase detection in SPR sensing, compare the performance of phase- and amplitude-sensitive sensors, review recent progress in the development and applications of phase-sensitive SPR sensors, and outline future prospects and trends of this technology

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Section: Surface Plasmon Resonance: Phase Vs Amplitudementioning

confidence: 99%

Phase‐sensitive surface plasmon resonance biosensors: methodology, instrumentation and applications

et al. 2012

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“…The most effective approach to the solution of the problem is two-plasmon spectroscopy when two plasmons are excited at different wavelengths [2,[4][5][6][7][8]. Different techniques for excitation have been applied [4][5][6][7][8] and each of them has specific drawbacks.…”

Section: Introductionmentioning

confidence: 99%

Plasmon Modes Management

2011

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A new plasmonic structure based on bimetallic layer is proposed. We analyze the structure and show that bimetallic film plays a crucial role in the management of surface plasmons. The roll of the buffer is discussed, as well. Up to three surface plasmons can be excited simultaneously in the structure. Two of plasmons can be used for two-plasmon spectroscopy. The third plasmon can be used for controlling the temperature of the structure.

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“…Metal-insulator-metal (MIM) waveguides have thus been a major focus of research in the recent years, as it can support (i) wide bandwidth and a range of mode shapes different than higher order waveguide modes, (ii) deep subwavelength capabilities (Our simulations show that penetration depth inside the metal is always below 25 nm, thus structures below 100 nm in width can be used), (iii) CMOS compatibility for fabrication, (iv) the possibility of very high density integration without cross-talk, (v) minimal Ohmic loss, (vi) while still keeping the unique advantages promised by optical waveguiding (WDM) 4 . These features make MIM highly attractive for high sensitivity spectroscopy applications and biosensing 5,6 , nonlinear optical phenomena 7,8 , waveguiding [9][10][11][12] , and on-chip signal routing, modulation and processing [13][14][15] .…”

Section: Introductionmentioning

confidence: 99%

Nanoantenna couplers for metal-insulator-metal waveguide interconnects

Onbaşlı

Okyay

2010

SPIE Proceedings

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State-of-the-art copper interconnects suffer from increasing spatial power dissipation due to chip downscaling and RC delays reducing operation bandwidth. Wide bandwidth, minimized Ohmic loss, deep sub-wavelength confinement and high integration density are key features that make metal-insulator-metal waveguides (MIM) utilizing plasmonic modes attractive for applications in on-chip optical signal processing. Size-mismatch between two fundamental components (micron-size fibers and a few hundred nanometers wide waveguides) demands compact coupling methods for implementation of large scale on-chip optoelectronic device integration. Existing solutions use waveguide tapering, which requires more than 4λ-long taper distances. We demonstrate that nanoantennas can be integrated with MIM for enhancing coupling into MIM plasmonic modes. Two-dimensional finite-difference time domain simulations of antennawaveguide structures for TE and TM incident plane waves ranging from λ = 1300 to 1600 nm were done. The same MIM (100-nm-wide Ag/100-nm-wide SiO2/100-nm-wide Ag) was used for each case, while antenna dimensions were systematically varied. For nanoantennas disconnected from the MIM; field is strongly confined inside MIM-antenna gap region due to Fabry-Perot resonances. Major fraction of incident energy was not transferred into plasmonic modes. When the nanoantennas are connected to the MIM, stronger coupling is observed and E-field intensity at outer end of core is enhanced more than 70 times.

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Multichannel surface plasmon resonance biosensor with wavelength division multiplexing

Cited by 131 publications

References 19 publications

Phase‐sensitive surface plasmon resonance biosensors: methodology, instrumentation and applications

Phase‐sensitive surface plasmon resonance biosensors: methodology, instrumentation and applications

Plasmon Modes Management

Nanoantenna couplers for metal-insulator-metal waveguide interconnects

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