Motor neuron diseases in the University Hospital of Fortaleza (Northeastern Brazil): a clinico-demographic analysis of 87 cases

Castro-Costa, Carlos Maurício de; Oriá, Reinaldo B.; Vale, Otoni Cardoso do; Arruda, José Arnaldo Motta de; Horta, Wagner G.; D'Almeida, José Artur Costa; Santos, Terezinha J.T.; Ramos, Rodrigo S.N.; Gifoni, Marcus A.C.

doi:10.1590/s0004-282x2000000600002

Cited by 15 publications

(10 citation statements)

References 18 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Regarding patient-related characteristics, we found no differences in mortality by gender. Other studies conducted in Brazil and in other Countries found that prevalence is increased in men relative to women [18][19][20] , although more recent reports suggest a decline in the gender ratio. This apparent discrepancy may be explained by the length of our study, by certain causal factors, by subtle differences in the natural history of the disease, or by the overall lower expectancy of life of men relative to women (69.1 vs. 77.2 in the studied population) 21 .…”

Section: Discussionmentioning

confidence: 81%

Mortality rates due to amyotrophic lateral sclerosis in São Paulo City from 2002 to 2006

Matos

Conde

Fávero

et al. 2011

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

OBJECTIVE: To describe the mortality rates of amyotrophic lateral sclerosis (ALS) in the city of São Paulo as a function of demographics, year, and region. METHOD: This was a retrospective descriptive study. Information was obtained from death certificates registered at the Program for the Improvement of Mortality Information, Municipal Health Department (PRO-AIM/SMS), coded as G12.2 according to International Classification of Diseases (ICD-10), from 2002 to 2006. RESULTS: Over the studied time, were found 326 deaths (51.6% women, overall mean age of 64.1 years). Highest deaths percentages happened in those from 60 to 69 and 70 to 79 years and in white individuals. ALS mortality rates ranged 0.44/100,000 in 2002 and 0.76/100,000 in 2006. No significant changes overtime in administrative districts were found. CONCLUSION: ALS mortality rates in São Paulo were lower in comparison to other countries, however any risk factor in our environment, lifestyle or genetic characteristics were found.

show abstract

Section: Discussionmentioning

confidence: 81%

Mortality rates due to amyotrophic lateral sclerosis in São Paulo City from 2002 to 2006

Matos

Conde

Fávero

et al. 2011

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

show abstract

“…O sintoma inicial na ELA, referido pelos pacientes como fraqueza em membros foi restrito a ELA clássica o que também confere com a literatura 22 , sendo as alterações da deglutição, voz e articulação em maior número de casos na forma bulbar em função da fraqueza e atrofia dos músculos controlados pelos NMS e NMI que envolvem a produção da palavra e a deglutição 5 .…”

Section: Discussionunclassified

Manifestações orofaríngeas na Esclerose Lateral Amiotrófica

Viana¹,

Alvarenga²

2015

Rev Neurocienc

View full text Add to dashboard Cite

original RESUMOObjetivo. Comparar as manifestações orofaríngeas de pacientes com as formas clássica e bulbar da ELA esporádica. Método. A avaliação fonoaudiológica de disfagia e disartrofonia seguiu a proposta de Casanova. Testou-se o movimento de lábio, língua, bochecha, pressão intra-oral, coordenação sucção/deglutição, pressão do esfíncter labial, mastigação, movimentação da língua, postura, mobilidade e força dos órgãos fonoarticulatórios. Resultados. 170 pacientes (56,47% homens e 59,41% brancos) com ELA bulbar (n= 66) e ELA clássica (n=104). As principais manifestações orofaríngeas foram as relacionadas a deglutição em 67,05%, seguindo-se a fonação 59,41% e a fala 51,76%. Conclusão. As manifestações orofaríngeas foram mais frequentes nos pacientes com a forma bulbar quando comparados à forma clássica. Unitermos. Esclerose lateral amiotrófica, Disartrofonia, DisfagiaCitação. Viana SMPO, Alvarenga RMP. Manifestações orofaríngeas na Esclerose Lateral Amiotrófica. ABSTRACTObjective. Compare the oropharyngeal manifestations of patients with classical and bulbar forms bulbar of sporadic ALS. Method. The speech therapy evaluation of dysphagia and dysarthrophonia followed the proposal of Casanova. Tested the movement of lip, tongue, cheek, oral cavity pressure, coordinating suction/swallow, pressure of lips, chewing, tongue movement, posture, mobility and strength of the articulators. Results. 170 patients (56.47% men and 59.41% white) were evaluated with bulbar ALS (n=66) and classic ALS (n=104). The major manifestations oropharyngeal were to swallow in 67.05%, phonation 59.41% and speech 51.76%. Conclusion. The oropharyngeal manifestations were significantly more frequent in patients with the bulbar form when compared to the classic form.

show abstract

“…In Brazil, the estimated prevalence varies from 0.9 to 1.5 cases/100,000 and the incidence varies from 0.2 to 0.32 cases per 100,000 inhabitants/year 5 . Previous studies have shown that men are twice as likely to suffer from ALS as women 6 and a Brazilian series 7 revealed a female to male ratio of 1:1.8. ALS is considered a paradigm of non-oncologic disease for palliative care 8 .…”

mentioning

confidence: 94%

Clinical attention and assistance profile of patients with amyotrophic lateral sclerosis

Lima

Nucci

2011

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

Objective: To evaluate the functional status of amyotrophic lateral sclerosis (ALS) patients diagnosed at this institution; to analyze hospital and palliative care; to identify patients' knowledge about home care and supportive resources. Method: Twenty-nine patients were evaluated on the ALSFRS-R scale and two semi-structured questionnaires, at the start of the study and every four months thereafter for 1 year. Results: ALSFRS-R score was 30.1±11.5 initially and 24.4±10.5 at 1 year. There was an increase in use of physiotherapeutic care and adaptive aids. The primary caregivers were spouses (55.2%), parents/children/cousins (20.7%), friends (10.3%) and private nurses (3.5%); 10.3% of patients had no caregivers. Basic ALS patient care was provided by the public health system. Conclusion: ALS patients' multidisciplinary care was provided by UNICAMP hospital and its outpatient clinics and, in some patients, complemented by a private health plan or personal expenditure. Few ALS patients were aware of the possibility of home nursing. It is necessary to implement national and regional public home nursing in addition to multidisciplinary specialized care of ALS patients. Key words: amyotrophic lateral sclerosis, ALSFRS-R scale, home nursing, caregivers, health system.Perfil clínico e assistencial de pacientes com esclerose lateral amiotrófica RESUMO Objetivo: Avaliar o estado funcional de um grupo de pacientes com esclerose lateral amiotrófica (ELA) na instituição; analisar a assistência hospitalar e de cuidados paliativos; identificar o conhecimento dos pacientes sobre potenciais recursos de assistência e home care. Método: Vinte e nove pacientes foram submetidos à escala ALSFRS-R e dois questionários semi-estruturados no início do estudo e a cada 4 meses, por um ano. Resultados: O escore inicial da ALSFRS-R foi 30,1±11,5 e o final 24,4±10,5, tendo sido necessária maior assistência fisioterápica e uso de órteses. O cuidador primário foi: cônjuge (55,2%), pais/filhos/primos (20,7%), amigos (10,3%), particular (3,5%); 10,3% não tinham cuidador. A assistência na ELA baseou-se no sistema público de saúde. Conclusão: O cuidado multidisciplinar ao paciente com ELA fez-se através do hospital e ambulatórios UNICAMP e, para alguns pacientes, houve complementação por plano de saúde e custeio pessoal. A maioria dos pacientes desconhecia a possibilidade de assistência domiciliar na ELA. Faz-se necessária a estruturação nacional e regional da assistência domiciliar pública em ELA, acrescida ao trabalho multidisciplinar especializado. Palavras-chave: esclerose lateral amiotrófica, escala ALSFRS-R, assistência domiciliar, cuidador, sistema de saúde.

show abstract

Motor neuron diseases in the University Hospital of Fortaleza (Northeastern Brazil): a clinico-demographic analysis of 87 cases

Cited by 15 publications

References 18 publications

Mortality rates due to amyotrophic lateral sclerosis in São Paulo City from 2002 to 2006

Mortality rates due to amyotrophic lateral sclerosis in São Paulo City from 2002 to 2006

Manifestações orofaríngeas na Esclerose Lateral Amiotrófica

Clinical attention and assistance profile of patients with amyotrophic lateral sclerosis

Contact Info

Product

Resources

About