The purpose is to explore the application and effect of scientific games based on artificial intelligence (AI) in preschool education under the smart city. An interactive scientific games model for children by virtual reality (VR) is constructed using the augmented reality (AR) technology in AI. This enables the product to continuously enrich its interactive functions in addition to realizing its own functional requirements, pay attention to user experience, and allow users to feel the pleasure and comfortable emotional communication brought by the product in the process of using it. The model mainly completes the interaction through gesture interaction and voice interaction, and it is further empirically analyzed by means of questionnaires and interviews. The results manifested that after the use of the intelligent interaction model of scientific games, 93.33% of the students in the experimental group were interested in scientific games, and 83.33% of the students in the experimental group had a clear understanding of scientific knowledge. Moreover, more students in the experimental group believed that they had received support from explanations, demonstrations, and guided conjectures, which was significantly different from the control group (P < 0.05). In the analysis of teacher interviews, it testified that the scientific values of preschool teachers and the reserve of basic scientific knowledge were still relatively weak, and their knowledge reserve could be improved in the future. Therefore, the research shows that the constructed model can improve the interest of scientific games and the ability of knowledge acquisition in preschool education, and provide an experimental reference for the development of intelligence and the improvement of teaching skills in the field of preschool education.