Motor evoked potentials and central motor conduction: studies of transcranial magnetic stimulation with recording from the leg

Effects of sex, height and age on motor evoked potentials with magnetic stimulation

“…Some investigators thus found that the CMCT was independent of both height and age [4,12,14], while others have reported that the CMCT is significantly affected by height and age [8,10,11]. Furthermore, the leg CMCT may correlate positively with height, while no difference was seen for the hand CMCT, even in the same subject group [8,11], and the same applied for gender difference.…”

“…It has previously been shown that MEP latencies positively correlate with height and age [4,8,10,11], but disagreements about the CMCT remain. Some investigators thus found that the CMCT was independent of both height and age [4,12,14], while others have reported that the CMCT is significantly affected by height and age [8,10,11].…”

“…The reliable identification of abnormal MEPs requires the statistical characterization of MEPs in an appropriate population of neurologically normal subjects. Based on previous studies, sex, height and age have all been clearly shown to influence the characteristics of MEPs [4,8,10,11]. However, most studies have concentrated on the 20-50-year age range, and there has been no comprehensive description of the normative results of hand and leg MEPs over a wide range of ages in a substantial sample of male and female subjects.…”

Motor Cortex Excitability in Patients with Migraine with Aura and Hemiplegic Migraine

“…By using TMS we have assessed the motor cortical excitability of patients with migraine with aura and familial hemiplegic migraine. We do not think that our results were affected by the age difference between patients and controls, since significant influence on TMS‐induced motor conduction has so far only been shown in subjects over the age of 60 years ( 24). In addition, in patients with MA and FHM age was not found to be a significant covariant factor for cortical excitability ( 18).…”

The amplitude of lower leg motor evoked potentials is a reliable measure when controlled for torque and motor task

“…However, this technique quantifies the severity of CS tract damage, while the present study investigates the influence of facilitation caused by background activity and motor task. No generally accepted reference values for TA MEP latency currently exist, although normal latencies appear to be around 30 ms (e.g., [32,33,[37][38][39][40]). In line with previous reports [37,40], a linear relationship between body height and MEP latency was found.…”