“…This possibility is supported by several findings: 1. nuclei of viruscontaining cells were apparently unchanged and did not differ substantially from those of healthy controls. By converse, it is known that rhabdoviruses with nuclear maturation often elicit recognizable nuclear alterations (KITAJIMA and COSTA 1966, RUBIO-HUERTOS and Bos 1969, MARTELLI 1969, CHEN and SHIKATA 1971, CHRISTIE et al 1974, Russo and MARTELLI 1975; 2. nucleocapsids or whole virions were not found in the nucleoplasm, nor CyRV particles were ever seen budding at the inner lamella of the nuclear envelope; 3. perinuclear accumulations of virus particles, so often encountered with rhabdoviruses maturing at the nuclear membrane, were absent; 4. in the rare instances when immature virions were found associated with the nuclear envelope, their coat was continuous with the outer rather than with the inner lamella of the envelope (fig.4), i.e. the particles were external to the caryoplasm; 5. structures having aspect and size comparable to that of internal components of virus particles were visualized in the cytoplasm.…”