Morphological Pattern of Childhood Solid Tumours in Lagos University Teaching Hospital.

Akinde, Olakanmi Ralph; Abdukareem, F B; Daramola, A O; Anunobi, C C; Banjo, A A F

doi:10.4314/nqjhm.v19i4.54512

Cited by 11 publications

(32 citation statements)

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“…This finding was very similar to reports from most part of Africa, [2][3][4][5][6][7][8][9] but different from reports from developed countries where leukemia's and intra cranial tumor predominate in children. [10] However, report by Ojesina et al, [11] from Ibadan reported a significant relative decline in the frequency of Burkitt's lymphoma which was ascribed the relative decline to the improved living conditions and greater control of malaria.…”

Section: Discussionsupporting

confidence: 85%

Pattern of childhood malignant tumors at a teaching hospital in Kano, Northern Nigeria: A prospective study

et al. 2014

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Background: Childhood cancers represent an important global public health problem. Survival is still dismal in most low income countries. Materials and Methods: A prospective study of childhood cancers diagnosed at AKTH, Kano was undertaken from January 2003 to December 2009 to determine the pattern, socio-economic and geographical features. Results: Malignant lymphomas constituted 46.5% of all cases, of which 30.1% were Burkitt's lymphoma, 9.8% were Non-Hodgkin (non Burkitt's) lymphoma and 6.6% were Hodgkin lymphoma. Retinoblastoma was the second most common malignancy constituting 15.2% of all cases, followed by Nephroblastoma 12.5% and acute leukemia's accounted for 14.1% of all cases. Others were Neuroblastoma 5.5%, Rhabdomyosarcoma 1.9% and CNS and Hepatissc tumors 4.3%. About 80% of parents of these children are very poor and could not afford the cost of treatment. Fifty one percent of the patients were alive at 12 months and the mortality was 24%. Conclusion: Childhood cancer is common in Kano. Free treatment is what is required since majority of the parents could not afford the cost of treatment.

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Section: Discussionsupporting

confidence: 85%

Pattern of childhood malignant tumors at a teaching hospital in Kano, Northern Nigeria: A prospective study

et al. 2014

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“…The predominance of Retinoblastoma among solid tumours in Lagos is similar to the finding in Ibadan which is in the same geopolitical zone. However, the very low frequency of Burkitt lymphoma (2%) in the most recent study from Lagos is a striking feature probably due to the fact that Akinde et al 29 used only histologically diagnosed cases and so excluded cytologically confirmed cases which might have included cases of Burkitt Lymphoma.…”

Section: Discussionmentioning

confidence: 99%

“…In the fifth centre, Zaria, Burkitt Lymphoma and Retinoblastoma were of equal frequency and ranked highest 27 . Out of the remaining two centres, Jos reported Rhabdomyosarcoma as the predominant solid tumour accounting for 31 percent of the tumours with Burkitt Lymphoma being the third most common and accounted for 13.8 percent of the tumours while in Lagos, Retinoblastoma was reported to be the predominant tumour and accounted for 21% of the tumours whereas Burkitt Lymphoma accounted for only 2% of the tumours 28,29 . …”

Section: Prevalencementioning

confidence: 98%

A review of the literature on childhood Burkitt lymphoma in Nigeria

B¹

2016

Nig. J. Paed.

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“…Retinoblastoma usually appears in children before the age of five years who had two alleles of the RB1 gene disease transmitted as on an autosomal dominant mode, and half of retinoblastoma is diagnosed before the age of two years (Packer et al, 2010). Holders of one diseased allele will have a non-ocular cancer increased risk (osteosarcoma in half of the cases) related to the RB gene (Icher et al, 2006;Akinde et al, 2009). In contrast, in some developed countries, neuroblastomas are the most common embryonic cancers with a rate of 44.43% in France for example (Bonet-Peris et al, 2006).…”

Section: 81 Evaluation Of the Histo-epidemiological Profile Of Solidmentioning

confidence: 99%

Evaluation of the Histo-Epidemiological Profile of Solid Childhood Cancers in Togo

Darré

Maneh²,

Boume³

et al. 2016

Asian Pacific Journal of Cancer Prevention

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Background: Cancer is a subject of continuing concern, more common in adults than in children, but often with a poor outcome in the latter. Our study set itself the objective to describe the epidemiological and histological aspects of solid cancers in children in Togo. Materials and Methods: This descriptive, cross-sectional study focused on cases of solid cancers in children diagnosed from 2010 to 2014 (5 years) at the pathology laboratory of the Tokoin teaching hospital. Data were collected from the records of that laboratory. Results: We collected 66 cases of childhood cancer representing 5% of all solid cancers. The annual incidence was 13.2 cases. The sex ratio (M/F) was 1.4; mean age was of 7.2±1.6 years. The age group most affected was that of 5-9 years (40.9%). Four histological groups of solid childhood cancers were listed: lymphoma (n=34 cases; 51.5%), embryonic cancer (n=17 cases; 25.8%), sarcomas (n=13 cases; 19.7%) and carcinoma (n=2 cases; 3%). The most common histological types were Burkitt lymphoma (36.4%), nephroblastoma (10.6%) and retinoblastoma (10.6%). Conclusions: This study shows that solid cancers in children are relatively frequent in Togo with a male predominance. They are still largely dominated by Burkitt lymphoma, followed by retinoblastoma and nephroblastoma.

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Morphological Pattern of Childhood Solid Tumours in Lagos University Teaching Hospital.

Cited by 11 publications

References 0 publications

Pattern of childhood malignant tumors at a teaching hospital in Kano, Northern Nigeria: A prospective study

Pattern of childhood malignant tumors at a teaching hospital in Kano, Northern Nigeria: A prospective study

A review of the literature on childhood Burkitt lymphoma in Nigeria

Evaluation of the Histo-Epidemiological Profile of Solid Childhood Cancers in Togo

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