Morphological Analysis in Patients With Sciatica

Zhang, Zhongwei; Song, Laijing; Quanfei, Meng; Li, Ziping; Pan, B.; Yang, Zhihua; Pei, Zhong

doi:10.1097/brs.0b013e318197162e

Cited by 54 publications

(7 citation statements)

References 25 publications

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“…DWIs and ADC maps of spinal nerve roots, ganglions, and nerves with generation of tractography [ 13 , 14 ] were shown to add value for the preoperative assessment of spinal nerve root lesions [ 15 , 16 ]. However, ADC values from the dorsal root ganglion in symptomatic patients were found to be inconsistent, but correlate with recovery from pain and numbness [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

Apparent diffusion coefficient maps in the assessment of surgical patients with lumbar spine degeneration

et al. 2017

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PurposeTo assess the utility of apparent diffusion coefficient (ADC) maps for the assessment of patients with advanced degenerative lumbar spine disease and describe characteristic features of ADC maps in various degenerative lumbar spinal conditions.MethodsT1-weighted, T2-weighted and diffusion weighted (DWI) MR images of 100 consecutive patients admitted to the spinal surgery service were assessed. ADC maps were generated from DWI images using Osyrix software. The ADC values and characteristic ADC maps were assessed in the regions of interest over the different pathological entities of the lumbar spine.ResultsThe study included 452 lumbar vertebral segments available for analysis of ADCs. Characteristic ADC map features were identified for protrusion, extrusion and sequester types of lumbar disk herniations, spondylolisthesis, reactive Modic endplate changes, Pfirrmann grades of IVD degeneration, and compromised spinal nerves. Compromised nerve roots had significantly higher mean ADC values than adjacent (p < 0.001), contralateral (p < 0.001) or adjacent contralateral (p < 0.001) nerve roots. Compared to the normal bone marrow, Modic I changes showed higher ADC values (p = 0.01) and Modic 2 changes showed lower ADC values (p = 0.02) respectively. ADC values correlated with the Pfirrmann grading, however differed from herniated and non-herniated disks of the matched Pfirrmann 3 and 4 grades.ConclusionQuantitative and qualitative evaluation of ADC mapping may provide additional useful information regarding the fluid dynamics of the degenerated spine and may complement standard MRI imaging protocol for the comprehensive assessment of surgical patients with lumbar spine pathology. ADC maps were advantageous in differentiating reactive bone marrow changes, and more precise assessment of the disk degeneration state. ADC mapping of compressed nerve roots showed promise but requires further investigation on a larger cohort of patients.

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Section: Discussionmentioning

confidence: 99%

Apparent diffusion coefficient maps in the assessment of surgical patients with lumbar spine degeneration

et al. 2017

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“…It should be noted that 3D DW PSIF is a sensitive sequence; it is prone to motion and ghosting artifacts. However, MIP reconstructions can enhance apparent SNR and be used to elegantly demonstrate nerves in multiple planes (Figure 4) [3, 6, 20]. Since it is a steady state sequence with both T1 and T2 contrasts, it shows neuropathy and mass lesions as abnormal T2 hyperintensity, with normal nerves appearing isointense to muscles, similar to other anatomic spin echo type sequences.…”

Section: Three-dimensional Anatomic Nerve-selective Mr Neurographymentioning

confidence: 99%

“…This is in part due to the rapid improvements in coil technology and software in the last few years [1–3]. With improved detection of nerve anatomy and pathology, the value of quantitative functional MR methods as potential biomarkers in neuromuscular disease is also being increasingly recognized [4].…”

Section: Introductionmentioning

confidence: 99%

MR Neurography: Advances

Chhabra

Zhao

Carrino

et al. 2013

Radiology Research and Practice

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High resolution and high field magnetic resonance neurography (MR neurography, MRN) is shown to have excellent anatomic capability. There have been considerable advances in the technology in the last few years leading to various feasibility studies using different structural and functional imaging approaches in both clinical and research settings. This paper is intended to be a useful seminar for readers who want to gain knowledge of the advancements in the MRN pulse sequences currently used in clinical practice as well as learn about the other techniques on the horizon aimed at better depiction of nerve anatomy, pathology, and potential noninvasive evaluation of nerve degeneration or regeneration.

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“…Normal nerves on 3D DWI-PSIF appear isointense to muscle, while nerve entrapment and resultant neuropathy are demonstrated by an increase in size and signal intensity proximal to the entrapment. 38,39 There have been no reports of quantitative evaluation of the GON signal and contrast characteristics in patients with occipital neuralgia (migraine), to our knowledge. Classically, the SNR has been defined as a measure comparing the level of a desired signal with the level of background noise of the image.…”

mentioning

confidence: 99%

MR Neurography of Greater Occipital Nerve Neuropathy: Initial Experience in Patients with Migraine

Hwang¹,

Dessouky

et al. 2017

AJNR Am J Neuroradiol

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Morphological Analysis in Patients With Sciatica

Abstract: The 3-dimensional DW-SSFP MRI with high spatial and sufficient contrast is an excellent technique to define the nature of sciatica and assists in prognostication and possibly in management.

Cited by 54 publications

References 25 publications

Apparent diffusion coefficient maps in the assessment of surgical patients with lumbar spine degeneration

Apparent diffusion coefficient maps in the assessment of surgical patients with lumbar spine degeneration

MR Neurography: Advances

MR Neurography of Greater Occipital Nerve Neuropathy: Initial Experience in Patients with Migraine

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