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2013
DOI: 10.4103/2229-5178.110639
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Morbihan syndrome

Abstract: We report a case of severe Morbihan syndrome (chronic erythematous edema of the upper portion of the face) in a 60-year-old man. The syndrome was characterized clinically by erythematous edema involving the forehead, glabella, and both eyelids, because of which the patient was not able to open completely his eyes. Furthermore, erythema and telangiectasiae were visible on the nose and cheeks. Laboratory and instrumental examinations were within normal ranges or negative. Histopathological examination showed der… Show more

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Cited by 42 publications
(68 citation statements)
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References 11 publications
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“…Marked infiltration of mast cells was observed in our case and in some previously reported cases (7,13), but not in other cases (1,2). The difference may depend on the stage of the disease and the way skin biopsies were taken.…”
Section: Successful Treatment Of Morbihan Disease With Long-term Minocontrasting
confidence: 70%
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“…Marked infiltration of mast cells was observed in our case and in some previously reported cases (7,13), but not in other cases (1,2). The difference may depend on the stage of the disease and the way skin biopsies were taken.…”
Section: Successful Treatment Of Morbihan Disease With Long-term Minocontrasting
confidence: 70%
“…The pathogenesis of Morbihan disease is still unclear; it is either considered as a rare latestage complication of rosacea/acne or as a distinct entity (2,4). There was no previous history of rosacea in our case.…”
Section: Discussionmentioning
confidence: 49%
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“…The edema worsens gradually over months to years with a solid consistency. The patient has no other symptomatic complaints and neither specific laboratory nor histopathologic findings have been observed [23]. The chronic nature of the skin condition, together with the restricted location, should differentiate this from angioedema.…”
Section: Resultsmentioning
confidence: 99%
“…Reported therapies include systemic corticosteroids, tetracyclines, isotretinoin, clofazimine and ketotifen. Excision of redundant edematous tissue is a surgical alternative treatment [21].…”
Section: Morbihan Diseasementioning
confidence: 99%