Monoclinic zirconia nanoparticle-catalyzed regioselective synthesis of some novel substituted spirooxindoles through one-pot multicomponent reaction in a ball mill: A step toward green and sustainable chemistry

A green synthesis of pyrimido[4,5-b]quinolines and pyrido[2,3-d]pyrimidines via a mechanochemical approach

“…As part of our ongoing research work to develop environmentally friendly methods for organic synthesis, [48][49][50][51][52][53][54][55] herein, we report for the first time our result for a nearly green synthesis protocol for pyrimido [4,5-b]…”

“…As part of our ongoing research work to develop environmentally friendly methods for organic synthesis, 48–55 herein, we report for the first time our result for a nearly green synthesis protocol for pyrimido[4,5- b ]quinolines and pyrimido[2,3- d ]pyrimidines via a one-pot multicomponent reaction of aromatic aldehyde, 6-aminouracil, and 1,3-diketo compounds under ball-milling conditions within a brief reaction time (Scheme 1(III a and b)).…”

Eco-Friendly and Facile Synthesis of Substituted Imidazoles via Nano Zirconia Catalyzed One-Pot Multicomponent Reaction of Isatin Derivatives with Ammonium Acetate and Substituted Aromatic Aldehydes under Solvent Free Conditions

“…In view of the above and as a part of our research group to synthesize the biologically active compounds [68][69][70][71][72], it was thought worthwhile to synthesize some novel imidazoles fused with indole nucleus of biocidal interest because the combination of two or more different heterocyclic compounds in a single molecule frequently increases the biocidal profile amazingly. With the aim of getting targeted products, i.e., substituted imidazole a greener "NOSE" (nanoparticles-catalyzed organic synthesis enhancement) approach has been designed under solvent-free conditions.…”