Monitoring of therapy in atopic dermatitis – observations with the use of high‐frequency ultrasonography

Abstract

This report shows the usefulness of HF-USG in monitoring tacrolimus therapy in atopic dermatitis. It is worth emphasizing, that this tool is easily reproducible and allows clinicians to visualize pathologic changes of all skin in vivo. As a noninvasive and independent of subjective judgment method, HF-USG should be included in overall evaluation of atopic dermatitis disease severity together with common scores or scales, especially in the era of evidence based medicine.

Polarized Light: A Conservative Therapeutic Approach to Chronic Hand Eczema

“…Ultrasound gel as a coupling medium was used and adjusted to be 1 mm to ensure efficiency. The printed paper from the device describes the thickness of the skin [19,20]. Determination of the severity of hand eczema: The hand is divided into 5 regions which are: the tips of the fingers, the fingers from the finger tips down to the knuckles, the palm, the dorsal aspect of the hand, and the wrist.…”

An ultrasonographic monitoring of skin condition in patients receiving radiotherapy for head and neck cancers

“…SLEB was previously described in such dermatoses as elastosis, atopic dermatitis, psoriasis, and mycosis fungoides. Its width reflects the thickness of the papillary dermis, which depends on the degree of vascularity, edema, and inflammatory cells infiltration . The SLEB was seen in 3 patients who presented maximum TLS: 4 (patient no 5), 3 (patient no 4), 2 (patient no 3) and interestingly in additional one patient in whom changes where subclinical as the TLS as well as CTCAE v 4.0 were assessed as 0 (patient no 2).…”

High‐frequency ultrasonography—New non‐invasive method in assessment of skin lymphomas

“…Skin ultrasonography is not a diagnostic method in MF because it cannot distinguish between similar images seen in inflammatory conditions such as atopic dermatitis or psoriasis. [7][8][9] Finally, the presence of SLEB may represent histopathological infiltration with T lymphocytes (Figure 3). Although this is only a hypothesis at present, our group is currently finalizing a study which appears to confirm this (manuscript under preparation).…”

“…Moreover, because ultrasound images allow for quantitative evaluation of treatment response, it can be used in numerous skin disorders, including inflammatory conditions (atopic dermatitis, psoriasis); it can also be used to guide therapeutic interventions in various dermatoses. [7][8][9][10] To date, the oncological use of HF-USG has mostly focused on melanoma and non-melanoma skin cancers, with only limited data available about its use in skin lymphomas. 6,11 To our knowledge, no studies have yet investigated the benefits of HF-USG in MF.…”