Monitoring cell viability in N-nitrosodiethylamine induced acute hepatitis and detection of hydrazine in solution and gas phase with Dual-function fluorescent probes

Small-molecule fluorescent probes for bioactive species in inflammatory disease: arthritis, pneumonia and hepatitis

“…26A) to monitor the esterase activity in NDEA-induced acute hepatitis and to detect N 2 H 4 in solution and gas-phase. 88 The probe was constructed with 4-hydroxy-1,8-naphthalimide with a large Stokes shift and large TP absorption cross section as the fluorophore, and acetyl group as the esterase recognition group. The maximum absorption of probe 29 red-shifted from 350 nm to 450 nm after the addition of esterase or N 2 H 4 .…”

Ratiometric SERS detection of N2H4 by porous Ag(i)-linked Waugh-type polyoxometalate as an efficient label-free substrate

“…26 Hydrazine (N 2 H 4 ) is widely used in industry, agriculture, aerospace and related fields due to its excellent physical and chemical properties. [27][28][29] However, N 2 H 4 is a highly toxic substance, and its excessive inhalation can lead to serious diseases. 30 At present, the detection of N 2 H 4 mainly includes electrochemical methods, fluorescence analysis and titration, etc.…”

A nucleophilic addition–elimination based ratiometric fluorescent probe for monitoring N2H4 in biological systems and actual samples

“…1,2 The widespread use of N 2 H 4 resulting in industrial waste containing hydrazine inevitably leads to water resource and soil pollution. 3,4 Furthermore, it accumulates in the environment and food chain, which poses a great threat to food safety, and seriously threatens human health and life. 5 In addition, although the human body cannot produce endogenous hydrazine, it is produced during the metabolism of some drugs.…”