Monitoramento do índice biespectral em cães

Guerrero, Piedad Natalia Henao; Nunes, Newton

doi:10.5433/1679-0359.2003v24n1p163

Cited by 4 publications

(3 citation statements)

References 12 publications

(14 reference statements)

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“…The signal was acquired with electrodes (Sensor; Aspect Medical Systems, Inc) placed as described by Guerrero and Nunes (2003 Next, a teflon catheter was placed percutaneously in the jugular vein to collect blood (3ml), which was collected into tubes containing ethylene-diamine-tetra-acetic acid (EDTA). The blood was submitted to laboratory evaluation (Abovet da ABX, abc Pach LMGE Montpellier, São Paulo, Brazil) to assess red blood cell count (He), hematocrit (Ht), hemoblogin concentration (Hb), platelets and total leukocytes count (Le).…”

Section: Methodsmentioning

confidence: 99%

Hematologic changes in propofol-anesthetized dogs with or without tramadol administration

Costa

Nunes

Belmonte

et al. 2013

Arq. Bras. Med. Vet. Zootec.

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Drugs commonly used in anesthesia practice may significantly alter the oxidative state of blood cells. This mechanism could contribute to the immune suppression that occurs transiently in the early postoperative period. Thus, we assessed the effects of continuous rate infusion (CRI) of propofol associated or not with tramadol on hematologic parameters in dogs. Eight adult mongrel dogs were anesthetized on 2 occasions, 15 d apart. Two groups were formed: control group (CG) and tramadol group (GT). Propofol was used for induction (10mg kg-1) followed by a CRI (0.7mg kg-1minute-1). The animals were positioned in lateral recumbency and mechanically ventilated with inspired oxygen fraction of 0.6. In TG, tramadol (2mg kg-1) followed by a CRI (0.5mg kg-1minute-1) was administered in dogs. In the CG the sodium chloride (NaCl) solution at 0.9% was administered followed by its CRI, in the same volume that was used in TG. The measurement was taken before anesthesia induction (Tbasal), 30 minutes after induction (T0) and then at 30-minute intervals (T30 to T60). Red blood cells, hematocrit, hemoblogin concentration and total leukocytes count decreased from T0 in both groups. In TG, lymphocytes count at Tbasal [1.86 (0.82) x103µl-1] was greater than at T0, T30 and T60 [0.96(0.50), 0.92(0.48) and 0.95(0.48) x103µl-1, respectively]. No significant differences were observed for platelets neutrophil, eosinophil, basophil and monocyte count. In dogs, propofol-anesthesia associated or not with tramadol promoted decrease in blood cell count and should be used with caution in immunossupressed patients.

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Section: Methodsmentioning

confidence: 99%

Hematologic changes in propofol-anesthetized dogs with or without tramadol administration

Costa

Nunes

Belmonte

et al. 2013

Arq. Bras. Med. Vet. Zootec.

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“…The BIS was computed by an Aspect A‐2000 monitor (Aspect Medical Systems, Inc, Natick, MA, USA). The signal was acquired with electrodes (BIS Sensor; Aspect Medical Systems, Inc) placed as described by Guerrero & Nunes (2003). The following data were recorded: BIS value, which is displayed as outlined numbers when the signal quality index (SQI) is <50, and in solid block form when the signal quality is adequate and >50; SQI, ranging from 0 to 100 .…”

Section: Methodsmentioning

confidence: 99%

Bispectral index in dogs at three intravenous infusion rates of propofol

Lopes

Nunes

Paula

et al. 2008

Veterinary Anaesthesia and Analgesia

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“…The value of BIS was assessed using BIS Vista 3.01 (Aspect Medical Systems Inc., Mansfield, MA02048, USA). First, electrodes (Covidien, Mansfield, MA 02048, USA) were positioned as described by Guerrero and Nunes [7]. Then, to ensure strong brainwave signals, signal quality index and electromyogram values were set at >30.…”

Section: Bis Measurementmentioning

confidence: 99%

Evaluation of the anesthetic depth and bispectral index during propofol sequential target-controlled infusion in dogs

et al. 2022

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Background and Aim: The use of anesthetic infusions based on pharmacokinetic values associated with anesthetic plan and bispectral index in dogs have not been well-documented in the literature. This study aimed to evaluate the bispectral index (BIS) change based on pre-propofol and establish clinical anesthetic depth changes during propofol sequential target-controlled infusion (STCI) in dogs with a plasma target of 5 μg/mL. Materials and Methods: Twenty healthy male dogs aged 1-3 years and weighing 9.8-44 kg were recruited. These dogs were pre-medicated intramuscularly with methadone (0.2 mg/kg) and acepromazine (0.03 mg/kg). After 30 min, propofol anesthetic induction and maintenance were initiated using STCI according to dog pharmacokinetic (PK) parameters. Subsequently, the target plasma concentration of propofol was set at 5 μg/mL for both anesthetic induction and the 120 min maintenance. Then, TivaTrainer v.9.1 software was used to calculate anesthetic infusion rates in a TCI plasmatic concentration mode using the PKs model optimized by covariates for propofol TCI in dogs. The BIS value was recorded every 5 min from the beginning of induction until the end of anesthesia. Finally, analysis of variance was performed on numerical data using the Friedman test, followed by the Bonferroni adjustment (p<0.05). Results: A statistical difference was observed between the baseline BIS value (T0), with a median value of 84.5 (81-97), and BIS after every 15 min (T15) of inducing anesthesia. Surgical anesthetic depth was also reached in 18 of 20 dogs after 10 min of infusion and in all dogs after 20 min, with a median BIS value of 72 (53-89) at the time of surgical anesthesia depth. Results also showed no BIS variation (p<0.05) between anesthetic moments after anesthetic induction with a substantial amplitude of BIS in the surgical anesthetic depth. Moreover, the maximum depth of anesthesia in all dogs by clinical evaluation was reached after 20 min of anesthesia and then remained stable throughout the anesthetic period. Conclusion: This study suggested that most dogs (90%) attained a surgical depth of anesthesia within 15 min of STCI onset, with a plasma target of 5 μg/mL and no change in anesthetic depth throughout the period anesthesia lasted. Furthermore, median BIS values remained high even after dogs reached the surgical depth of anesthesia, indicating that the comparison of BIS values of dogs and humans should not be considered for classifying anesthetic and hypnotic depths in dogs.

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Monitoramento do índice biespectral em cães

Cited by 4 publications

References 12 publications

Hematologic changes in propofol-anesthetized dogs with or without tramadol administration

Hematologic changes in propofol-anesthetized dogs with or without tramadol administration

Bispectral index in dogs at three intravenous infusion rates of propofol

Evaluation of the anesthetic depth and bispectral index during propofol sequential target-controlled infusion in dogs

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