Momordica cochinchinensis Seed Extracts Suppress Migration and Invasion of Human Breast Cancer ZR-75-30 Cells Via Down-regulating MMP-2 and MMP-9

Momordica cochinchinensis (L.) Spreng: Aril Extract Prevents Adverse Reproductive Parameters of Male Rats Induced with Valproic Acid

“…In further studies, the biochemical and molecular analyses will be performed to explain additional mechanisms of how the MC could prevent such adverse effects. The protective tissue damage effect demonstrated in this study is a phytotherapeutic property of MC extract besides other pharmacological properties shown in previous reports (Zheng et al;Jung et al, 2013aJung et al, , 2013bLiu et al;Chuethong et al;Tien et al;Kang et al;Tsoi et al;Xiao et al, 2007Xiao et al, , 2009Rajput et al, 2007Rajput et al, , 2010. Moreover, MC extract indeed did not affect any male reproductive parameters including testicular histology as compared to the control.…”

“…Recently, various scientific studies have shown that MC fruit extract has antioxidant and pharmacological properties (Kubola & Siriamornpun, 2011). MC has been demonstrated to have anti-cancer activities (Zheng et al, 2014;Jung et al, 2013a;Liu et al, 2012;Chuethong et al, 2007;Tien et al, 2005). In addition, it was also reported for its anti-inflammatory effect (Jung et al, 2013b) and angiogenesis (Kang et al, 2010).…”

Sex-oriented research on dioecious crops of Indian subcontinent: an updated review

“…seed pulp, for the availability of considerably more carotenoid, the ripe gac (M. cochinchinensis) fruit is massively used to colour the rice grains by the Vietnamese (Aoki et al 2002;Vuong et al 2006). Zheng et al (2014) proved the anticancerous property of gac seeds. In India, sweet gourd or gac fruit is an underutilized vegetable but the other three are popularly known as kantola or spine gourd or teasle gourd and fruit; young twigs as well as leaves are widely consumed as vegetables.…”

Saponins from Rubus parvifolius L. Induce Apoptosis in Human Chronic Myeloid Leukemia Cells through AMPK Activation and STAT3 Inhibition

“…Plant-derived phytochemicals have been used as therapeutic agents for hundreds of years (Zheng et al, 2014). Natural products from plants have been proven to be a rich resource for anticancer drug discovery.…”