Molluscum contagiosum eyelid lesions in an HIV-patient

Massa, António Fernandes; Borges‐Costa, João; Soares‐Almeida, Luís; Sacramento-Marques, Manuel

doi:10.5070/d32dc3w4mb

Cited by 9 publications

(9 citation statements)

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“…They have a basophilic appearance and measure approximately 25 micrometers in diameter [ 15 , 16 , 17 ]. Through electron microscopic investigations, it has been observed that these inclusions encase MCV within membrane-bound structures, often composed of aggregates of nuclear and cytoplasmic aggregates and proteins [ 4 , 15 , 18 ]. These inclusion bodies serve as the sites for viral replication [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

Eyelid Lesion of Molluscum Contagiosum: A Case Report and Literature Review

Chaurasia,

Rastogi,

Maddheshiya

et al. 2024

Cureus

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Molluscum contagiosum (MC) is a common viral infection in children that affects the skin and oral mucous membranes. It is caused by the molluscum contagiosum virus (MCV), a double-stranded DNA virus in the Poxviridae family. Transmission takes place via direct skin contact, self-inoculation, and exposure to contaminated objects. Clinically, it is characterized by the presence of a single or multiple enlarged dome-shaped or doughnut-shaped flesh-colored papules with central umbilication, usually called "mollusca". The diagnosis of MC is based mainly on clinical observations, in addition to histopathological examinations to reveal characteristic molluscum bodies, also known as Henderson-Patterson bodies. Current treatment methods include mechanical, chemical, immune modulation, and antiviral treatments. In this context, we present a case involving a 42-year-old male infected with MC, outlining both the clinical and histopathological findings.

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Section: Discussionmentioning

confidence: 99%

Eyelid Lesion of Molluscum Contagiosum: A Case Report and Literature Review

Chaurasia,

Rastogi,

Maddheshiya

et al. 2024

Cureus

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“…Facial molluscum and fungal infections can be marker of severe immunosuppression in HIV patients and FNAC diagnosis can help in treatment planning. [15] Of ten malignancies two were basal cell carcinoma (BCC), two squamous cell carcinoma, three sebaceous carcinomas, one adenoid cystic carcinoma, one micro cystic adnexal carcinoma of lacrimal gland and one diffuse large B cell lymphoma with deposits in lid Table 1 Cases of BCC showed basaloid cells with palisading on cytology, of which one showed prominent pigmentation which was later confirmed histologically as pigmented BCC. (Figure 6 A-E) Case of conjunctival ulcero-proliferative lesion was aspirated using non aspiration technique as well as scrape was taken and was diagnosed as squamous cell carcinoma.…”

Section: Discussionmentioning

confidence: 99%

Role of Aspiration Cytology in Intraocular and Periorbital Adnexal Lesions

Gupta¹,

Bhat²,

Nayak³

et al. 2021

JMSH

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Introduction: Ophthalmic pathology including orbital, intraocular, and periorbital is unique. Wide spectrum of infections and neoplasia; benign as well as malignant are seen in this area. Many neoplastic conditions mimic non-neoplastic inflammatory conditions and needs differentiation before definitive therapy. Cytology is a simple, safe and fairly accurate technique for differentiating inflammatory from neoplastic and benign from malignant conditions thus avoiding more invasive surgical biopsies in these delicate areas. Present study was aimed to evaluate the role of fine needle aspiration as a tool in diagnosis of intra orbital and peri ocular adnexal lesions. Material and Method: FNAC was performed in a series of 20 patients presenting with intra orbital and peri ocular adnexal masses after clinical and radiological evaluation. Smears were analysed by a cytologist and histopathological confirmation was done as indicated. Results :The age ranged from 19 to 70 years. Male: Female ratio was 11:9. Of 20 cases, 03; 04; 03; 10 were infective, benign cystic lesions, benign neoplastic and malignant respectively. Of malignancies 02; 03; 02; 01; 01; 01 were of basal cell carcinoma, sebaceous carcinoma, squamous cell carcinoma, adenoid cystic carcinoma, micro cystic adnexal carcinoma and diffuse large B cell lymphoma respectively. Confirmation was done in 16 /20 cases. Concordance rate of FNAC with histologic diagnosis was 100% in broadly classifying them into infective, benign cystic, benign neoplastic and malignant neoplastic pathology. However, histopathology and Flow cytometry was helpful in subclassifying them in select cases.

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“…describieron la relación entre MC palpebral en pacientes con VIH y el recuento bajo de linfocitos T CD4+ 11 . Se considera que el MC es la infección viral del párpado más común en pacientes con SIDA 11 y puede ser la manifestación inicial de la enfermedad 12 .…”

Section: Discussionunclassified

“…Según la clasificación clínica de Rosner y Zloto 4 , los dos pacientes que reportamos corresponden a las variantes MC conglomerado (Figura 1) y MC nodular umbilicado (Figura 3), dos presentaciones que han sido descritas en pacientes inmunosuprimidos, y en las que la biopsia no solo es útil para confirmar el diagnóstico, sino que permite descartar otras dermatosis infecciosas graves, que cursan con manifestaciones clínicas similares o pueden coexistir junto a la lesión de MC, como la histoplasmosis y la criptococosis 12 .…”

Section: Discussionunclassified

Molusco contagioso del párpado: manifestación cutánea de inmunosupresión

Morales-Cardona

Romero-Porras

2021

Infect

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El molusco contagioso es una infección viral cutánea, usualmente benigna y autolimitada, causada por un virus del género Molluscipoxvirus. Es más frecuente en niños, adultos jóvenes sexualmente activos e inmunosuprimidos. La lesión clínica característica es una pápula umbilicada eucrómica o de tono perlado, que se disemina rápidamente y puede afectar cualquier superficie muco-cutánea, aunque la localización en los párpados es atípica. Se presentan dos casos de pacientes jóvenes inmunosuprimidos, con moluscos contagiosos palpebrales, en quienes el diagnóstico clínico inicial fue incorrecto. Se enfatiza la importancia de diagnosticar oportunamente las lesiones papulares que afectan la piel del párpado ya que la presencia de molusco contagioso en esta zona se considera una manifestación cutánea de inmunosupresión.

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Molluscum contagiosum eyelid lesions in an HIV-patient

Cited by 9 publications

References 0 publications

Eyelid Lesion of Molluscum Contagiosum: A Case Report and Literature Review

Eyelid Lesion of Molluscum Contagiosum: A Case Report and Literature Review

Role of Aspiration Cytology in Intraocular and Periorbital Adnexal Lesions

Molusco contagioso del párpado: manifestación cutánea de inmunosupresión

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