Molecularly imprinted polymers as receptors for assays of antibiotics

A chitosan gold nanoparticles molecularly imprinted polymer based ciprofloxacin sensor

“…Molecular imprinting technique is also the substitute of natural receptors and successfully used as an articial analytical receptor for molecular identication with binding properties as natural antibodies in immunoassays. 10,11 Therefore, MIPs are termed as plastic anti-bodies. Literature reveals that including biological structure more than 10 000 molecules such as inorganic ions, drugs, cells, nucleic acid, protein, and viruses have been imprinted successfully.…”

High throughput molecularly imprinted polymers based electrochemical nanosensors for point-of-care diagnostics of COVID-19

“…This raises the demand for the artificial recognition element which can mimic the BRESs and can selectively detect the analyte. [11] , [12] . The main properties of MIPs and the various templates used for MIPs along with the published literature are depicted in Fig.…”

Employing molecularly imprinted polymers in the development of electroanalytical methodologies for antibiotic determination

“…Polymerization can be oversimplified as a step consisting in submitting a solution containing a FM and the template to heat, UV or an applied potential (the former occurs at higher temperatures which is disadvantageous since the strength of ionic and hydrogen interactions with the template is lower 32 ), where the FMs polymerize around the template forming an artificial fabric holding the analyte. Typically, cross‐linker and radical initiator molecules are required in heat and UV‐assisted polymerization (photopolymerization), while in electropolymerization they are not necessary.…”

“…The template removal step consists in extracting the leftover template from the polymer matrix, and that is often challenging 32,108 . Frequently it is done by washing the MIP with a solution in which the template is adequately soluble and can easily detach from the polymer for a determined amount of time and, in some cases, stirring 73,75 .…”

“…Antibiotics are divided into classes based on its origin, structure and mechanisms of microbialaction 138‐140 . Several studies use molecular imprinting technology to determine antibiotics in different environments, 32 such as biological samples, food samples and effluents as shown in Tables 1 and 2.…”