Molecular characterization and evolution analysis of five interleukin-17 receptor genes in large yellow croaker Larimichthys crocea

RNA‐Seq analysis of the guppy immune response against Gyrodactylus bullatarudis infection

“…These receptors are constitutively expressed in several tissues and organs, including high constitutive expression in mucosal tissues of the gills and skin 55,63,64 . Moreover, gill mucosal tissue, along with the lymphoid organs of the head kidney and spleen, showed upregulation of IL‐17 receptors in L. crocea infected with Aeromonas hydrophila (see Ding et al 54 ), in line with our observation of increased IL‐17 receptor expression in the skin of infected guppies.…”

“…Genes related to known IL‐17 family members and IL‐17 receptors have been identified in other teleosts 53,54 . IL‐17 homologues, for example, have been found in the genomes of zebrafish ( Danio rerio ), fugu ( Takifugu spp.…”

“…Th17 is also involved in T-cell polarization in response to infection by extracellular and intracellular bacteria and fungi 52. Genes related to known IL-17 family members and IL-17 receptors have been identified in other teleosts 53,54. IL-17 homologues, for example, have been found in the genomes of zebrafish (Danio rerio), fugu (Takifugu spp.…”

“…IL-17 homologues, for example, have been found in the genomes of zebrafish (Danio rerio), fugu (Takifugu spp. ), grass carp and salmonids,[55][56][57][58][59][60][61][62] while five IL-17Rs were found in the large yellow croaker (Larimichthy scrocea) 54. These receptors are constitutively expressed in several tissues and organs, including high constitutive expression in mucosal tissues of the gills and skin 55,63,64.…”

Genomic Signatures After Five Generations of Intensive Selective Breeding: Runs of Homozygosity and Genetic Diversity in Representative Domestic and Wild Populations of Turbot (Scophthalmus maximus)

“…Hypoxia tolerance, when interacting with water temperature and salinity, has a major impact on fish physiology, including growth and immune response in aquaculture conditions (Lund et al, 2017), and has been associated with selection signatures in the channel catfish (Sun et al, 2014). Genome mining of this region also revealed other immune-related genes, such as ifsf21a, which belongs to a family of membrane receptors, and il17rd, which encodes a component of the interleukin receptor 17 and associated with immune response against bacterial pathogens in fish mucosal tissues (Wang et al, 2014;Ding et al, 2016).…”