Modulation of hepatic ABC transporters by Eruca vesicaria intake: Potential diet-drug interactions

Roma, Martín Ignacio; Lampropulos, Victoria E. Schiariti; Ayllón-Cabrera, Iván; Sanabria, Ana N. Salazar; Nigro, Marcela M. López; Peroni, Roxana N.; Carballo, Marta A.

doi:10.1016/j.fct.2019.110797

Cited by 5 publications

(1 citation statement)

References 63 publications

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“…Cruciferous plants have some phytochemicals protective against DNA damage such as sulforaphane erusine and erysoline. Rocket diet could increase hepatic ABC transporters' expression which reduces the risk of toxic compounds (Roma et al 2019). Rocket is widely spread all over the world (Barillari et al 2005).…”

Section: Introductionmentioning

confidence: 99%

Disodyum oktaborat tetrahidratın (DOT) Roka (Eruca sativa Mill.) ve Tere (Lepidium sativum L.)'de tohum çimlenmesi ve gelişimi üzerine etkileri

Erkan

Aşcı

2022

Bilge International Journal of Science and Technology Research

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Rocket (Eruca sativa Mill.) is cultivated throughout the year. Thanks to the rich metabolites of its leaves, it has a wide usage area in pharmacy. Cress (Lepidium sativum) is in the group of annual vegetables and has a herbaceous structure. Due to its fragrant and slightly spicy structure, it is a vegetable that is used as an appetizer. Its seeds and green parts are very beneficial for health. Rocket is a short-day plant whose leaves are considered to be rich in many minerals and vitamins. The present research was conducted to investigate the effects of doses of Disodium octaborate tetrahydrate (DOT) (0 (control), 15, 30, 45, 60 mg L -1 on the germination and development of seeds of rocket and cress plants grown in pot experiments. In order to determine the effect of DOT on the development and yield of rocket and cress plants, the percentage of germinated seeds, cotyledon length and dry matter amounts were determined. ANOVA test was used to analyze the data obtained in the present study. Tukey test was used to determine which groups were in significant differences between the groups. Overall, it was seen that there were significant growth differences between the doses used statistically, the particularly 45 mg L -1 application DOT positively affected the germination and dry matter content of rocket and cress seeds.

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Section: Introductionmentioning

confidence: 99%

Disodyum oktaborat tetrahidratın (DOT) Roka (Eruca sativa Mill.) ve Tere (Lepidium sativum L.)'de tohum çimlenmesi ve gelişimi üzerine etkileri

Erkan

Aşcı

2022

Bilge International Journal of Science and Technology Research

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ABCB1 in dermatology: roles in skin diseases and their treatment

Weng

Tsai

2021

J Mol Med

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Adenosine triphosphate–binding cassette subfamily B member 1 (ABCB1), also known as permeability glycoprotein, multidrug-resistant protein 1, or cluster of differentiation 243 (CD243), is a crucial protein for purging foreign substances from cells. The functions of ABCB1 have been investigated extensively for their roles in cancer, stem cells, and drug resistance. Abundant pharmacogenetic studies have been conducted on ABCB1 and its association with treatment responsiveness to various agents, particularly chemotherapeutic and immunomodulatory agents. However, its functions in the skin and implications on dermatotherapeutics are far less reported. In this article, we reviewed the roles of ABCB1 in dermatology. ABCB1 is expressed in the skin and its appendages during drug delivery and transport. It is associated with treatment responsiveness to various agents, including topical steroids, methotrexate, cyclosporine, azathioprine, antihistamines, antifungal agents, colchicine, tacrolimus, ivermectin, tetracycline, retinoid acids, and biologic agents. Moreover, genetic variation in ABCB1 is associated with the pathogenesis of several dermatoses, including psoriasis, atopic dermatitis, melanoma, bullous pemphigoid, Behçet disease, and lichen planus. Further investigation is warranted to elucidate the roles of ABCB1 in dermatology and the possibility of enhancing therapeutic efficacy through ABCB1 manipulation.

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Synthesis and antitumor activity of erysolin and its metabolites

Zhao

Zhou

et al. 2022

Journal of Asian Natural Products Research

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Modulation of hepatic ABC transporters by Eruca vesicaria intake: Potential diet-drug interactions

Cited by 5 publications

References 63 publications

Disodyum oktaborat tetrahidratın (DOT) Roka (Eruca sativa Mill.) ve Tere (Lepidium sativum L.)'de tohum çimlenmesi ve gelişimi üzerine etkileri

Disodyum oktaborat tetrahidratın (DOT) Roka (Eruca sativa Mill.) ve Tere (Lepidium sativum L.)'de tohum çimlenmesi ve gelişimi üzerine etkileri

ABCB1 in dermatology: roles in skin diseases and their treatment

Synthesis and antitumor activity of erysolin and its metabolites

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