Modified indium tin oxide electrodes: Electrochemical applications in pharmaceutical, biological, environmental and food analysis

Silah, Hülya; Erkmen, Cem; Demir, Ersin; Uslu, Bengi

doi:10.1016/j.trac.2021.116289

Cited by 32 publications

(25 citation statements)

References 94 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among them, TCO films are the most widely utilized transparent electrodes due to their flexibility, high uniformity, large-scale fabrication, and the fact that they are a mature technology [ 7 , 8 ]. Typical TCO transparent electrodes are InSnO (ITO) films, which have been commercialized for more than three decades [ 9 ]. However, scarcity of the metal element In will inevitably cause a critical issues of rising cost and manufacture unsustainability [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Investigation on Transparent, Conductive ZnO:Al Films Deposited by Atomic Layer Deposition Process

et al. 2022

View full text Add to dashboard Cite

Transparent electrodes are a core component for transparent electron devices, photoelectric devices, and advanced displays. In this work, we fabricate fully-transparent, highly-conductive Al-doped ZnO (AZO) films using an atomic layer deposition (ALD) system method of repeatedly stacking ZnO and Al2O3 layers. The influences of Al cycle ratio (0, 2, 3, and 4%) on optical property, conductivity, crystallinity, surface morphology, and material components of the AZO films are examined, and current conduction mechanisms of the AZO films are analyzed. We found that Al doping increases electron concentration and optical bandgap width, allowing the AZO films to excellently combine low resistivity with high transmittance. Besides, Al doping induces preferred-growth-orientation transition from (002) to (100), which improves surface property and enhances current conduction across the AZO films. Interestingly, the AZO films with an Al cycle ratio of 3% show preferable film properties. Transparent ZnO thin film transistors (TFTs) with AZO electrodes are fabricated, and the ZnO TFTs exhibit superior transparency and high performance. This work accelerates the practical application of the ALD process in fabricating transparent electrodes.

show abstract

Section: Introductionmentioning

confidence: 99%

Investigation on Transparent, Conductive ZnO:Al Films Deposited by Atomic Layer Deposition Process

et al. 2022

View full text Add to dashboard Cite

show abstract

“…According to the discussion illustrated above, quantification, detection, and separation of TAM in biological fluids and pharmaceutical formulations have been followed by researchers. For this goal, various analytical techniques including high-performance liquid chromatography (HPLC), gas chromatography (GC), nonaqueous capillary electrophoresis, potentiometry, GC-mass spectrometry, polarography, single sweep voltammetry, and spectrophotometry have been used. − Compared to the mentioned analytical techniques, electrochemical methods are more important to analytical chemists for analyzing various compounds containing electroactive functional groups due to their excellent advantages such as low cost, high sensitivity, and relatively short analysis time. − Accordingly, introducing novel catalysts/compounds with simple/eco-friendly synthesis procedures for various chemical applications has great interest. − Thus, electrochemical methods have adopted great application in detecting and determining various compounds such as pharmaceutics and biomolecules. − Anticancer drugs have OH and NH 2 electroactive functional groups, which can generate electroanalytical signals due to electrooxidation or due to oxidative cyclization reactions . To enhance selectivity, sensitivity, and other characteristics of the electrode, surface modification of electrodes has been used.…”

Section: Introductionmentioning

confidence: 99%

Cyclic and Linear Sweep Voltammetric Studies of a Modified Carbon Paste Electrode with Nickel Oxide Nanoparticles toward Tamoxifen: Effects of Surface Modification on Electrode Response Kinetics

2022

View full text Add to dashboard Cite

Due to the serious adverse futures of some anticancer drugs, the determination of trace amounts of these drugs by simple analytical techniques is of great interest. In this regard, knowing about the mechanism of the analyte with the sensing material plays an important role. Nickel oxide nanoparticles (NiO NPs) modified by a carbon paste electrode (NiO-CPE) showed an irreversible cyclic voltammetric (CV) behavior in the NaOH (pH 13) supporting electrolyte based on the peak separation of 311 mV. Its peak current was decreased by adding tamoxifen (TAM), confirming that TAM molecules can consume NiO before participating in the electrode reaction. For this goal, TAM can be oxidized or reduced, and the corresponding mechanisms are schematically illustrated in the text. This study focused on the kinetic aspects of the process. Based on the CV results, a surface coverage (Γ) value of 2.72 × 10 –5 mol NiO per cm 2 was obtained with charge transfer coefficients α a and α c of 0.317 and 0.563, respectively. α a and α c values were changed to 0.08 and 0.72 in the presence of TAM. Further, the rate constant ( k s ) value was 0.021 ± 0.01 s –1 in the presence of TAM. In linear sweep voltammetry (LSV), an α value of about 0.636 ± 0.023 and an exchange rate constant ( k o ) value of about 0.097 ± 0.031 s –1 were obtained in the absence of TAM, which changed to 0.62 ± 0.081 and 0.089 ± 0.021 s –1 in the presence of TAM, respectively. Despite more published papers, when the TAM analyte was added to the NaOH supporting electrolyte, both anodic and cathodic peak currents of the modified NiO-CPE decreased. We suggested some reasons for this decreased peak current, and four mechanisms were illustrated for the electrode response in the presence of TAM.

show abstract

“…One approach to overcome the described shortcomings is the use of electrochemical sensors since most of these drugs are electroactive substances. Electrochemical sensors can provide advantages, such as being cheap and easy to use, having low detection limits, wide linear response ranges, good stability, reproducibility, direct detection of analyte, easy sample preparation, and the possibility of miniaturization [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Voltammetric Determination of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Using a Modified Carbon Paste Electrode and Chemometrics

Aguilar-Lira

López-Barriguete

Hernández³

et al. 2022

Sensors

View full text Add to dashboard Cite

This work presents the simultaneous quantification of four non-steroidal anti-inflammatory drugs (NSAIDs), paracetamol, diclofenac, naproxen, and aspirin, in mixture solutions, by a laboratory-made working electrode based on carbon paste modified with multi-wall carbon nanotubes (MWCNT-CPE) and Differential Pulse Voltammetry (DPV). Preliminary electrochemical analysis was performed using cyclic voltammetry, and the sensor morphology was studied by scanning electronic microscopy and electrochemical impedance spectroscopy. The sample set ranging from 0.5 to 80 µmol L−1 was prepared using a complete factorial design (34) and considering some interferent species such as ascorbic acid, glucose, and sodium dodecyl sulfate to build the response model and an external randomly subset of samples within the experimental domain. A data compression strategy based on discrete wavelet transform was applied to handle voltammograms’ complexity and high dimensionality. Afterward, Partial Least Square Regression (PLS) and Artificial Neural Networks (ANN) predicted the drug concentrations in the mixtures. PLS-adjusted models (n = 12) successfully predicted the concentration of paracetamol and diclofenac, achieving correlation values of R ≥ 0.9 (testing set). Meanwhile, the ANN model (four layers) obtained good prediction results, exhibiting R ≥ 0.968 for the four analyzed drugs (testing stage). Thus, an MWCNT-CPE electrode can be successfully used as a potential sensor for voltammetric determination and NSAID analysis.

show abstract

Modified indium tin oxide electrodes: Electrochemical applications in pharmaceutical, biological, environmental and food analysis

Cited by 32 publications

References 94 publications

Investigation on Transparent, Conductive ZnO:Al Films Deposited by Atomic Layer Deposition Process

Investigation on Transparent, Conductive ZnO:Al Films Deposited by Atomic Layer Deposition Process

Cyclic and Linear Sweep Voltammetric Studies of a Modified Carbon Paste Electrode with Nickel Oxide Nanoparticles toward Tamoxifen: Effects of Surface Modification on Electrode Response Kinetics

Simultaneous Voltammetric Determination of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Using a Modified Carbon Paste Electrode and Chemometrics

Contact Info

Product

Resources

About