Ultrasonic curing of one-part epoxy system was studied using differential scanning calorimetry (DSC) analysis. During both isothermal oven curing and ultrasonic curing of this system, an induction period was observed. For the rapid progression of polymerization reaction in ultrasonic curing, a preheating temperature of 100 C was found to be sufficient. However, degree of curing due to the nonthermal effect of ultrasonic curing was found to be maximal at a preheating temperature of 80 C. It was noticed that the ultrasonic curing reduced the time of curing by a factor of four, and the curing level from pure thermal effects could be determined by incorporating the curing temperature history into the autocatalytic chemical model. The degree of curing from the experimental results of isothermal heating in DSC and the one predicted by the autocatalytic chemical model exhibited a good agreement.