Modeling of melt electrospinning for semi-crystalline polymers

Zhmayev, Eduard; Cho, Daehwan; Joo, Yong Lak

doi:10.1016/j.polymer.2009.11.025

Cited by 83 publications

(57 citation statements)

References 37 publications

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“…Initially, the extruded polymer melt at the tip of the nozzle is like a truncated spherical droplet which changes its shape after the introduction of the electric field. Though there are geometrical models for electrospinning process such as Taylor cone as a frustum and straight jet as a cylinder are discussed in literature [5,8,21,22,25]. In our modeling, the jet pulled out from droplet is geometrically defined as a funnel as shown in Figure 1 which consists of a cone whose tip is removed surmounted on a narrow cylinder is discussed.…”

Section: Geometrical Modelingmentioning

confidence: 99%

“…Although brilliant results have been achieved in terms of microstructure physical properties such as crystallinity, there is a need to design more practical models to control the desired microstructure topographical properties of electrospun fibers. For instance, Zhmayev and Joo have a model which analyzese the polymer melt behaviour of nylon through its flow induced crystallization properties [22,23]. In another work by Zhmayev, the stable jet region in melt electrospinning has been reported [22].…”

Section: Introductionmentioning

confidence: 99%

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Using mathematical modeling to control topographical properties of poly (ε-caprolactone) melt electrospun scaffolds

Bhullar

Mohtaram

et al. 2014

J. Micromech. Microeng.

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Melt electrospinning creates fibrous scaffolds using direct deposition. The main challenge of melt electrospinning is controlling the topography of the scaffolds for tissue engineering applications. Mathematical modeling enables a better understanding of the parameters that determine the topography of scaffolds. The objective of this study is to build two types of mathematical models. First, we modeled the melt electrospinning process by incorporating parameters such as nozzle size, counter electrode distance and applied voltage that influence fiber diameter and scaffold porosity. Our second model describes the accumulation of the extruded microfibers on flat and round surfaces using data from the microfiber modeling. These models were validated through the use of experimentally obtained data. Scanning electron microscopy (SEM) was used to image the scaffolds and the fiber diameters were measured using Quartz-PCI Image Management Systems® in SEM to measure scaffold porosity.

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Section: Geometrical Modelingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Using mathematical modeling to control topographical properties of poly (ε-caprolactone) melt electrospun scaffolds

Bhullar

Mohtaram

et al. 2014

J. Micromech. Microeng.

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“…Therefore, in the case of a Taylor (Lee et al, 2011) vortex, the shear and elongation stress from the pair of oppositely rotating vortices align the solute molecules while they move in a radial direction. Such flow-induced nucleation was already observed in the melt spinning of polymers (Zhemayev et al, 2010), where a high shear during melt spinning initiated polymer nucleation, resulting in a high crystalline polymer product. Thus, the induction of stable crystals with a Taylor vortex occurred within 8 h at a low rotation speed of 300 rpm and within 4 h when increasing the rotation speed to 1,000 rpm.…”

Section: Phase Transformation With Taylor Vortexmentioning

confidence: 60%

Application of Taylor Vortex to Crystallization

Kim

2014

J. Chem. Eng. Japan / JCEJ

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This study summarizes crystallization technology when using a Taylor vortex ow. A Taylor vortex is created in the gap between two co-axially positioned cylinders based on the rotation of the inner cylinder. Due to its unique periodic ow motion, a Taylor vortex has a signi cant in uence on the processes of nucleation, growth, and agglomeration breakage in various crystallizations, including reaction recrystallization, drowning-out crystallization, and cooling crystallization. In the gas-liquid reaction crystallization of calcium carbonate, the mass transfer at the gas-liquid interface is greatly facilitated by a Taylor vortex, resulting in small crystals with a uniform size and morphology. Further, due to molecular alignment by the periodic Taylor vortex motion, the polymorphic nucleation of stable crystals is also promoted. This e ect of molecular alignment by a Taylor vortex is demonstrated by the phase transformation of sulfamerazine. Furthermore, the Taylor vortex ow in a Taylor crystallizer improves the productivity of crystallization when compared with the random turbulent eddy ow in an MSMPR crystallizer. Consequently, the high performance of a Taylor crystallizer using a Taylor vortex has strong potential for application to various crystallizations.

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“…Mathematical modelling approaches can be used to predict the topographical dependency of microfiber scaffolds on various operational parameters for better understanding of melt electrospinning technique through the use of numerical studies and comparing the results with experimental data [17,22,25,26]. We have previously shown that the topographical properties of melt eletcrsopun scaffolds had directed stem cell differentiation into neural phenotypes [9].…”

Section: Discussionmentioning

confidence: 99%

“…To achieve a scaffold that provides specific mechanical and topographical properties, mathematical models have been developed to predict the effect of key operational parameters such as nozzle size, temperature, collecting distance and applied voltage on controlling the fiber size and porosity [17,[25][26][27]. Although melt electrospining has shown its promising potential in tissue engineering applications, controlling scaffold topography, however, still remains challenging [9,14,20,21].…”

Section: Introductionmentioning

confidence: 99%

Mathematical model for predicting topographical properties of poly (ε-caprolactone) melt electrospun scaffolds including the effects of temperature and linear transitional speed

Mohtaram

Lee

et al. 2015

J. Micromech. Microeng.

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Melt electrospinning can be used to fabricate various fibrous biomaterial scaffolds with a range of mechanical properties and varying topographical properties for different applications such as tissue scaffold and filtration and etc., making it a powerful technique. Engineering the topography of such electrospun microfibers can be easily done by tuning the operational parameters of this process. Recent experimental studies have shown promising results for fabricating various topographies, but there is not that body of work that focuses on using mathematical models of this technique to further understand the effect of operational parameters on these properties of microfiber scaffolds. In this study, we developed a novel mathematical model using numerical simulations to demonstrate the effect of temperature, feed rate and flow rate on controlling topographical properties such as fiber diameter of these spun fibrous scaffolds. These promising modelling results are also compared to our previous and current experimental results. Overall, we show that our novel mathematical model can predict the topographical properties affected by key operational parameters such as change in temperature, flow rate and feed rate and this model could serve as a promising strategy for the controlling of topographical properties of such structures for different applications.

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Modeling of melt electrospinning for semi-crystalline polymers

Cited by 83 publications

References 37 publications

Using mathematical modeling to control topographical properties of poly (ε-caprolactone) melt electrospun scaffolds

Using mathematical modeling to control topographical properties of poly (ε-caprolactone) melt electrospun scaffolds

Application of Taylor Vortex to Crystallization

Mathematical model for predicting topographical properties of poly (ε-caprolactone) melt electrospun scaffolds including the effects of temperature and linear transitional speed

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