Misdiagnosis of Hydrophilic Acrylic Intraocular Lens Optic Opacification

Haymore, Jonathan; Zaidman, Gerald W.; Werner, Liliana; Mamalis, Nick; Hamilton, Stephan; Cook, James; Gillette, Thomas E.

doi:10.1016/j.ophtha.2006.12.024

Cited by 31 publications

(24 citation statements)

References 18 publications

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“…Nd:YAG laser treatment is ineffective in removing the calcified deposits from the lenses (1,(3)(4)(5) , as seen in most of our cases. The only effective treatment to restore vision is explantation and exchange of the calcified IOL.…”

Section: Discussionmentioning

confidence: 57%

“…This patient's second IOL was placed in the sulcus. Former studies have described other postoperative complications, such as posterior capsule opacification, cystoid macular edema, retinal detachment, choroidal hemorrhage and endophthalmitis (4,5,14) . Although hydrophilic acrylic IOLs have higher uveal biocompatibility resulting in less postoperative inflammation than other IOLs (18) , (Lots starting with: A09, A10, B09, C09, D09, E09, F09, G08, G09, H08, H09, I08, I09, J08, J09, K08, k09, L08, L09).…”

Section: Discussionmentioning

confidence: 99%

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Microscopic analysis of opacification in Ioflex® hydrophilic acrylic intraocular lenses

Ventura

Lira

et al. 2012

Rev. bras.oftalmol.

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Five cases of intraocular lens (IOL) opacification in patients implanted with the Mediphacos Ioflex® IOL are described. Clinical data in each case was obtained from the patient's medical record. The five explanted IOLs underwent gross and light microscopic analysis. Selected lenses were processed for further evaluation and multiple sagittal cuts were stained with the alizarin red and von Kossa methods. Light microscope analysis confirmed the presence of deposits on and within the lens, which stained positive for calcium. The reason why calcification has occurred in these cases remains unclear, but surgeons should be aware of this potential late postoperative complication.Keywords: Lenses, intraocular; Lens implantation, intraocular; Reoperation; Device removal; Microscopy; Case reports RESUMO Cinco casos de opacificação de lente intraocular (LIO) em pacientes implantados com a LIO Ioflex® da Mediphacos são descritos. Os dados clínicos dos pacientes foram obtidos a partir dos prontuários médicos. As cinco LIOs explantadas foram enviadas para análise macroscópica e sob microscopia óptica. Algumas lentes foram processadas para análise adicional e múltiplos cortes sagitais foram corados pelos métodos de vermelho de alizarina e von Kossa. A análise sob microscopia óptica confirmou a presença de depósitos na superfície e no corpo da lente, que coraram positivamente para cálcio. A razão pela qual a calcificação ocorreu nestes casos permanece obscura. Entretanto, cirurgiões devem estar atentos para esta potencial complicação tardia.Descritores: Lentes intraoculares; Implante de lenteintraocular; Reoperação; Remoção de dispositivo; Microscopia; Relatos de casos 1 Fundação Altino Ventura -FAV -Recife (PE), Brazil;

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Section: Discussionmentioning

confidence: 57%

Section: Discussionmentioning

confidence: 99%

Microscopic analysis of opacification in Ioflex® hydrophilic acrylic intraocular lenses

Ventura

Lira

et al. 2012

Rev. bras.oftalmol.

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“…In some cases, the deposits causing the opacification are found on the optical surface/subsurface of the lenses, while they are predominantly found within the optic substance in others. [4][5][6][7] In cases of calcification of silicone lenses in eyes with asteroid hyalosis, studies demonstrated deposits only on the posterior optic surface of the lenses. The deposits could be partially removed with Nd:YAG laser, but there was a reaccumulation after the procedure because the asteroid bodies are rich in calcium/phosphate.…”

Section: Discussionmentioning

confidence: 99%

Effects of Intraocular Lens Opacification on Light Scatter, Stray Light, and Overall Optical Quality/Performance

Werner

Stover

Schwiegerling

et al. 2016

Invest. Ophthalmol. Vis. Sci.

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“…It is critical to recognize the process involved in IOL opacification; otherwise, surgeons might perform unnecessary surgical procedures such as neodymium:YAG (Nd:YAG) posterior capsulotomies or vitrectomies in eyes in which the opacification is in the IOL itself and not in the posterior capsule or vitreous. 3,4 LABORATORY FINDINGS Gross examination of the explanted IOLs showed a white discoloration of the specimens. Microscopic examination showed dense deposits forming an almost continuous crust, mostly on the anterior surface of the optic component.…”

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confidence: 99%