Purpose: To evaluate the incidence of posterior capsule opacification (PCO) four years after the implantation of a hydrophilic acrylic intraocular lens (IOL). Methods: Fifty-eight randomly selected eyes from 58 patients were analyzed four years after phacoemulsification and Ioflex IOL implantation. The patients underwent an ophthalmic examination to detect PCO and a detailed medical history was obtained. The patients' charts were reviewed for their corrected distance visual acuity prior to the IOL implantation, as well as for one month postoperatively. The Student's t-test was used for statistical analysis. Results: The mean age of patients without PCO was 74.6 ± 9.5 years, compared to 70.3 ± 15 years in patients with PCO. Four years after surgery, 39 of the 58 eyes (67%) had detectable PCO and 24 eyes (41.3%) had decreased visual acuity (VA) due to PCO. These patients were referred for Nd:YAG laser capsulotomy. Three patients (5.1%) had decreased VA due to glaucoma, IOL opacification, or age-related macular degeneration. Twelve eyes (20.7%) presented mild PCO with unchanged VA. Systemic arterial hypertension was reported by 45% of the patients, and in 3.5% of these cases this was associated with diabetes mellitus. Conclusion: This study found the incidence of PCO to be 67% four years after phacoemulsification and Ioflex IOL implantation.

Intraocular lens opacification was observed in 7% of the eyes studied. No risk factors could be determined.

Five cases of intraocular lens (IOL) opacification in patients implanted with the Mediphacos Ioflex® IOL are described. Clinical data in each case was obtained from the patient's medical record. The five explanted IOLs underwent gross and light microscopic analysis. Selected lenses were processed for further evaluation and multiple sagittal cuts were stained with the alizarin red and von Kossa methods. Light microscope analysis confirmed the presence of deposits on and within the lens, which stained positive for calcium. The reason why calcification has occurred in these cases remains unclear, but surgeons should be aware of this potential late postoperative complication.Keywords: Lenses, intraocular; Lens implantation, intraocular; Reoperation; Device removal; Microscopy; Case reports RESUMO Cinco casos de opacificação de lente intraocular (LIO) em pacientes implantados com a LIO Ioflex® da Mediphacos são descritos. Os dados clínicos dos pacientes foram obtidos a partir dos prontuários médicos. As cinco LIOs explantadas foram enviadas para análise macroscópica e sob microscopia óptica. Algumas lentes foram processadas para análise adicional e múltiplos cortes sagitais foram corados pelos métodos de vermelho de alizarina e von Kossa. A análise sob microscopia óptica confirmou a presença de depósitos na superfície e no corpo da lente, que coraram positivamente para cálcio. A razão pela qual a calcificação ocorreu nestes casos permanece obscura. Entretanto, cirurgiões devem estar atentos para esta potencial complicação tardia.Descritores: Lentes intraoculares; Implante de lenteintraocular; Reoperação; Remoção de dispositivo; Microscopia; Relatos de casos 1 Fundação Altino Ventura -FAV -Recife (PE), Brazil;

Gross examination was performed and gross pictures were recorded using a digital camera (D40 with a 55 mm lens, Nikon Corp., Tokyo, Japan). The unstained specimen was evaluated and photographed under a light microscope

OBJECTIVE: To evaluate clinical features of patients related to opacification of hydrophilic acrylic intraocular lenses, four years after surgery. METHODS: We evaluated six cases of late opacification of Ioflex intraocular lenses (case group) compared to 24 patients (control group) with no opacification. Both groups underwent phacoemulsification as a result of a community campaign for underprivileged people. Patients who underwent bilateral cataract surgery had only the right eye included on the study. The patients were submitted to ophthalmic examination, including measurements of corrected distance visual acuity and biomicroscopy slitlamp evaluation. Detailed medical histories were obtained. Surgical details were retrieved. RESULTS: Systemic arterial hypertension was recorded in 4 patients from the case group and 11 in the control group, with no statistically significant difference between groups. A single patient in the control group had diabetes mellitus, and so was not considered for statistical analysis. No environmental factor could be related. There were no statistically significant differences for mean visual acuity between the groups of patients regarding the evaluation periods. One eye in the control group received an Ioflex intraocular lens with the same lot number as one of the opacified lenses. CONCLUSION: No clear patient factor could be related to late Ioflex lens opacification.

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RESUMOIntrodução: A ceratoplastia penetrante autóloga ipsilateral rotacional pode ser uma alternativa para minimizar o problema de longas filas de espera para transplante por ceratocone. Objetivo: Apresentar os resultados visuais em portadores de ceratocone após ceratoplastia penetrante autóloga ipsilateral rotacional associada à ressecção de 0,5 mm de crescente corneana inferior. Métodos: Estudo prospectivo, longitudinal, de intervenção, analítico, investigando os resultados visuais de 15 pacientes (18 olhos), com diagnóstico de ceratocone, submetidos a ceratoplastia penetrante autóloga ipsilateral rotacional (CPAIR) por meio de duas trepanações, coincidentes superiormente e com diferença de 0,5 mm inferiormente. Após ressecção da cunha resultante das duas trepanações inferiores, o disco corneano foi rotado de 180° e suturado com 24 pontos diametralmente opostos. Os pacientes foram acompanhados por um período de 24 meses. Resultados: Ao comparar os dados de 1º e 2º anos de pós-operatório aos do pré-operatório, observou-se melhora significante de: acuidade visual, linhas de visão, equivalente esférico, diminuição do astigmatismo topográfico e das curvaturas corneais máxima e média. Houve adelgaçamento corneano, com diminuição do número de células endoteliais da córnea. Conclusão: Observou-se melhora dos parâmetros oftalmológicos decorridos 6, 12 e 24 meses da ceratoplastia penetrante autóloga ipsilateral rotacional associada à ressecção de 0,5 mm na porção inferior corneana, mas ao longo do seguimento houve redução da acuidade visual com aumento do astigmatismo. Descritores