Miniaturized hollow fiber assisted liquid-phase microextraction and gas chromatography–mass spectrometry for the measurement of progesterone in human serum

Kawaguchi, Migaku; Takatsu, Akiko

doi:10.1016/j.jchromb.2008.12.022

Cited by 22 publications

(8 citation statements)

References 27 publications

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“…The mixture is injected directly into a GC system . Recently described applications of these techniques for drug analysis are summarized in Table .…”

Section: Lpmementioning

confidence: 99%

Microextraction sample preparation techniques in biomedical analysis

Szultka

Pomastowski

Railean-Plugaru

et al. 2014

J of Separation Science

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Biologically active compounds are found in biological samples at relatively low concentration levels. The sample preparation of target compounds from biological, pharmaceutical, environmental, and food matrices is one of the most time-consuming steps in the analytical procedure. The microextraction techniques are dominant. Metabolomic studies also require application of proper analytical technique for the determination of endogenic metabolites present in biological matrix on trace concentration levels. Due to the reproducibility of data, precision, relatively low cost of the appropriate analysis, simplicity of the determination, and the possibility of direct combination of those techniques with other methods (combination types on-line and off-line), they have become the most widespread in routine determinations. Additionally, sample pretreatment procedures have to be more selective, cheap, quick, and environmentally friendly. This review summarizes the current achievements and applications of microextraction techniques. The main aim is to deal with the utilization of different types of sorbents for microextraction and emphasize the use of new synthesized sorbents as well as to bring together studies concerning the systematic approach to method development. This review is dedicated to the description of microextraction techniques and their application in biomedical analysis.

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“…The mixture is injected directly into a GC system . Recently described applications of these techniques for drug analysis are summarized in Table .…”

Section: Lpmementioning

confidence: 99%

Microextraction sample preparation techniques in biomedical analysis

Szultka

Pomastowski

Railean-Plugaru

et al. 2014

J of Separation Science

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“…34% of summarized applications were bioanalytical methods for the determination of drugs in various biological materials aside from environmental and food applications. Recently, HF-LPME has been employed in the analysis of xenobiotics nitrophenols in human plasma [148], the anti-diabetic drug pioglitazone in plasma [149], the antidepressants amitryptilin, imipramine and sertraline in urine and plasma samples [150], flunitrazepam in plasma and urine samples [151], progesterone in human serum [152] as well as ␤-agonists and ␤-antagonists in urine [153] and many others. Both HPLC and GC methods were used for the final analysis.…”

Section: Liquid-liquid Microextraction (Llme)mentioning

confidence: 99%

A review of current trends and advances in modern bio-analytical methods: Chromatography and sample preparation

Nováková

Vlčková

2009

Analytica Chimica Acta

497

231

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“…To date, numerous LPME [10][11][12][13] and DLLME [14] methods have been applied for bioanalysis in various matrices. One of the main areas of considerable research interest is the possible integration of different steps (e.g., preconcentration, derivatization and sample cleanup) into a single one.…”

Section: Simultaneous Extraction and Derivatizationmentioning

confidence: 99%