Mindfulness-based therapy for inflammatory bowel disease patients with functional abdominal symptoms or high perceived stress levels

Abstract

NCT01426568.

Effect of psychological therapy on disease activity, psychological comorbidity, and quality of life in inflammatory bowel disease: a systematic review and meta-analysis

“…Of these, a further 32 were excluded for various reasons leaving 14 studies eligible for data extraction. [23][24][25][26][27][28][29][30][31][32][33][40][41][42] Agreement between reviewers for eligibility assessment was excellent (Kappa statistic = 0.91). Detailed study characteristics are provided in Table 1, and risk of bias across all studies is reported in page 1 of the webappendix.…”

“…[23][24][25][26][27][28][29]32,33,[40][41][42] . Four of these presented data in patients with CD, 25,32,40,42 four in patients with UC, 27,28,40,41 and five in patients with IBD.…”

“…Four of these presented data in patients with CD, 25,32,40,42 four in patients with UC, 27,28,40,41 and five in patients with IBD. 23,24,26,29,33 Results from all analyses in patients with quiescent IBD are summarised in Table 2.…”

“…One study included CD patients, 42 three studies included UC patients, 27,28,41 and two included patients with IBD. 24, 29 Overall, 159 (57.4%) of 277 patients treated with psychological therapy experienced a relapse of disease activity, compared with 127 (52.7%) of 241 patients in the control group. Compared with control, the RR of relapse of disease activity in all patients with IBD treated with psychological therapy was 0.98 (95% CI 0.77 to 1.24) (Figure 2).…”

“…22 However, the authors included quasirandomised and non-randomised studies in their analysis and there have been numerous additional studies published in the intervening years. [23][24][25][26][27][28][29][30][31][32][33] We therefore aimed to re-examine the efficacy of psychological therapies in IBD, with particular emphasis on their effects on disease activity indices, psychological wellbeing, including anxiety, depression, and perceived stress, and quality of life.…”