Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease

Sinopoulou, Vassiliki; Gordon, Morris; Akobeng, Anthony K; Gasparetto, Marco; Sammaan, Michael; Vasiliou, Jessica; Dovey, Terence M.

doi:10.1002/14651858.cd013531.pub2

Cited by 18 publications

(16 citation statements)

References 52 publications

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“…Dyspareunia, pelvic pain, bowel obstruction, and adhesion-related disorder (ARD) with consequent depression and anxiety could be associated with dense or firm intraperitoneal adhesion formation. Crohn's disease is characterized by abdominal pain and surgical complications such as strictures and adhesions [16]. Obesity (BMI > 25 kg/m2) and multiple laparotomies are also additional risk factors for intestinal injury during the lysis of adhesions in repeated surgeries [17].…”

Section: Discussionmentioning

confidence: 99%

Extraperitoneal Cesarean Section after two Medial Laparotomies, Anus Prater, and Surgical Treatment of the Rectovaginal Fistula in a Patient with Crohn’s Disease: A Case Report

Bačić,

Hrgović,

Cerovac

et al. 2023

Z Geburtshilfe Neonatol

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The aim of this case report is to show the advantages of the extraperitoneal cesarean section (ECS) approach in a pregnant patient with multiple previous abdominal transperitoneal colon surgeries and Crohn’s disease. A pregnant nulliparous woman with Crohn’s disease was admitted for delivery. After delivery, a large rupture and lesion of the rectum was observed. Suturing of the vagina, rectum and sphincter was performed by an abdominal surgeon. Because of a very large and irregularly shaped rectum rupture, the patient underwent infraumbilical medial laparotomy and sigmoidostomy. After 18 months, the patient started to experience vaginal discharge and Y-shaped rectovaginal fistula was confirmed. Surgical reconstruction was performed. The patient’s second pregnancy began one year later. At 38 weeks of pregnancy, elective extraperitoneal cesarean section was performed. A healthy newborn was delivered. Follow-up showed full and fast recovery after the ECS. In cases of pregnant women who have had multiple colon surgeries, gynecology surgeons can choose to perform an ECS to avoid transperitoneal entrance into the abdomen. ECS avoids lysis of postoperative adhesions after repetitive gastrointestinal surgeries, the formation of new adhesions by lysis of the old adhesions, and most importantly, the possibility of colon or small intestine lesions during lysis of dense or firm adhesions.

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Section: Discussionmentioning

confidence: 99%

Extraperitoneal Cesarean Section after two Medial Laparotomies, Anus Prater, and Surgical Treatment of the Rectovaginal Fistula in a Patient with Crohn’s Disease: A Case Report

Bačić,

Hrgović,

Cerovac

et al. 2023

Z Geburtshilfe Neonatol

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“…Reducing the intake of foods high in FODMAPs can reduce the frequency of adverse reactions such as abdominal distension and pain ( 68 ). Although the LFD cannot alleviate the intensity of abdominal pain episodes in both CD and UC, showing a limited therapeutic effect in active patients ( 69 , 70 ), studies have demonstrated that the LFD markedly reduces the probability of progression to an active stage in patients with IBD in remission ( 71 ). Therefore, following the LFD dietary pattern in IBD remission can help to maintain intestinal homeostasis and improve the quality of life of patients to a certain extent.…”

Section: Modified Dietary Advice Based On Dietary Patterns and Custom...mentioning

confidence: 99%

Comparison and recommendation of dietary patterns based on nutrients for Eastern and Western patients with inflammatory bowel disease

Hou

Wang²,

Zhou³

et al. 2023

Front. Nutr.

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Inflammatory bowel disease (IBD), a non-specific chronic idiopathic inflammatory condition of the digestive system, requires lifelong treatment in which drugs are the mainstay, along with surgery when necessary. In adjuvant therapies, the diet is considered to be an essential, controllable, and economical component. However, the majority of recent nutrition research has focused on the general effects of nutrients on IBD, with little attention given to the advantages and negative aspects of individual foods and dietary combinations. To cover these shortcomings, we surveyed the benefits and drawbacks of typical foods and their chemical compositions on intestinal pathophysiology by comparing nutrients existing in the foods in Eastern and Western countries. Moreover, for Eastern and Western patients with IBD, we innovatively propose a 3-step dietary recommendation based on modified customary eating habits, including lowering the triggering foods, modifying dietary advice to control disease progression, and improving surgery prognosis.

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“…Crohn's disease (CD) can affect any section of the digestive tract, in addition to diarrhea and abdominal pain 4 . Over time, many patients with fecal incontinence will experience chronic pain, depression, anxiety, and embarrassment 5,6 . IBD is becoming more commonplace worldwide, especially in recently industrialized nations, and is linked to a substantial lifelong sickness burden 7 …”

Section: Introductionmentioning

confidence: 99%

“…4 Over time, many patients with fecal incontinence will experience chronic pain, depression, anxiety, and embarrassment. 5,6 IBD is becoming more commonplace worldwide, especially in recently industrialized nations, and is linked to a substantial lifelong sickness burden. 7 Erythema nodosum (EN) is a skin disease that typically affects the lower extremities and is characterized by inflammation of the subcutaneous fatty tissue.…”

Section: Introductionmentioning

confidence: 99%

Causal relationship between inflammatory bowel disease and erythema nodosum: A two‐sample bidirectional Mendelian randomization study

Zhu,

Jiang,

et al. 2024

Skin Research and Technology

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BackgroundPrevious studies have demonstrated the coexistence of erythema nodosum (EN) and inflammatory bowel disease (IBD), while the exact etiology of the co‐occurrence of the two disorders remains uncertain.MethodsA bidirectional two‐sample Mendelian randomization (MR) design was employed to determine the causal link between EN and IBD. Genetic variations associated with Crohn's disease (CD) and ulcerative colitis (UC) were derived from accessible genome‐wide association studies pertaining to European ancestry. The FinnGen database was used to find the genetic variations containing EN. In the forward model, IBD was identified as the exposure, whereas in the reverse model, EN was identified as the exposure. The causal link between IBD and EN was examined using a range of different analysis techniques, the primary one being the inverse variance weighted (IVW) method, including inverse variance weighted‐fixed effects (IVW‐FE) and inverse‐variance weighted‐multiplicative random effects (IVW‐MRE). To strengthen the results, assessments of sensitivity, heterogeneity, and pleiotropy were also conducted.ResultsMR results showed that IBD increased the risk of EN (IVW‐MRE: OR = 1.242, 95% CI = 1.068–1.443, p = 0.005). Furthermore, there was a strong correlation found between CD and a higher risk of EN (IVW‐FE: OR = 1.250, 95% CI = 1.119–1.396, p = 8.036 × 10−5). However, UC did not appear to be linked to EN (IVW‐FE: OR = 1.104, 95% CI = 0.868–1.405, p = 0.421). The reverse MR analysis findings did not imply that EN was linked to IBD. Horizontal pleiotropy did not appear to exist, and the robustness of these findings was confirmed.ConclusionThe current investigation found that in European populations, IBD and its subtype CD could raise the incidence of EN.

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Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease

Abstract: Trusted evidence. Informed decisions. Better health.

Cited by 18 publications

References 52 publications

Extraperitoneal Cesarean Section after two Medial Laparotomies, Anus Prater, and Surgical Treatment of the Rectovaginal Fistula in a Patient with Crohn’s Disease: A Case Report

Extraperitoneal Cesarean Section after two Medial Laparotomies, Anus Prater, and Surgical Treatment of the Rectovaginal Fistula in a Patient with Crohn’s Disease: A Case Report

Comparison and recommendation of dietary patterns based on nutrients for Eastern and Western patients with inflammatory bowel disease

Causal relationship between inflammatory bowel disease and erythema nodosum: A two‐sample bidirectional Mendelian randomization study

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