Interventions for the management of abdominal pain in ulcerative colitis

Iheozor‐Ejiofor, Zipporah; Gordon, Morris; Akobeng, Anthony K

doi:10.1002/14651858.cd013589.pub2

Cited by 12 publications

(9 citation statements)

References 61 publications

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“…Reducing the intake of foods high in FODMAPs can reduce the frequency of adverse reactions such as abdominal distension and pain ( 68 ). Although the LFD cannot alleviate the intensity of abdominal pain episodes in both CD and UC, showing a limited therapeutic effect in active patients ( 69 , 70 ), studies have demonstrated that the LFD markedly reduces the probability of progression to an active stage in patients with IBD in remission ( 71 ). Therefore, following the LFD dietary pattern in IBD remission can help to maintain intestinal homeostasis and improve the quality of life of patients to a certain extent.…”

Section: Modified Dietary Advice Based On Dietary Patterns and Custom...mentioning

confidence: 99%

Comparison and recommendation of dietary patterns based on nutrients for Eastern and Western patients with inflammatory bowel disease

Hou

Wang²,

Zhou³

et al. 2023

Front. Nutr.

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Inflammatory bowel disease (IBD), a non-specific chronic idiopathic inflammatory condition of the digestive system, requires lifelong treatment in which drugs are the mainstay, along with surgery when necessary. In adjuvant therapies, the diet is considered to be an essential, controllable, and economical component. However, the majority of recent nutrition research has focused on the general effects of nutrients on IBD, with little attention given to the advantages and negative aspects of individual foods and dietary combinations. To cover these shortcomings, we surveyed the benefits and drawbacks of typical foods and their chemical compositions on intestinal pathophysiology by comparing nutrients existing in the foods in Eastern and Western countries. Moreover, for Eastern and Western patients with IBD, we innovatively propose a 3-step dietary recommendation based on modified customary eating habits, including lowering the triggering foods, modifying dietary advice to control disease progression, and improving surgery prognosis.

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Section: Modified Dietary Advice Based On Dietary Patterns and Custom...mentioning

confidence: 99%

Comparison and recommendation of dietary patterns based on nutrients for Eastern and Western patients with inflammatory bowel disease

Hou

Wang²,

Zhou³

et al. 2023

Front. Nutr.

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“…This may occur by integrating microbiome sciences with metabolomics and epigenetics [83,94]. Understanding the contribution of each microbial kingdom to host-microbe interactions could significantly improve the management of UC and support opportunities for personalized medicine [95].…”

Section: Saccharomyces Cerevisiae Andmentioning

confidence: 99%

Microbiota-Immune Interactions in Ulcerative Colitis and Colitis Associated Cancer and Emerging Microbiota-Based Therapies

Popov

Caputi

Nandeesha

et al. 2021

IJMS

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Ulcerative colitis (UC) is a chronic autoimmune disorder affecting the colonic mucosa. UC is a subtype of inflammatory bowel disease along with Crohn’s disease and presents with varying extraintestinal manifestations. No single etiology for UC has been found, but a combination of genetic and environmental factors is suspected. Research has focused on the role of intestinal dysbiosis in the pathogenesis of UC, including the effects of dysbiosis on the integrity of the colonic mucosal barrier, priming and regulation of the host immune system, chronic inflammation, and progression to tumorigenesis. Characterization of key microbial taxa and their implications in the pathogenesis of UC and colitis-associated cancer (CAC) may present opportunities for modulating intestinal inflammation through microbial-targeted therapies. In this review, we discuss the microbiota-immune crosstalk in UC and CAC, as well as the evolution of microbiota-based therapies.

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“…Given that UC is a chronic condition with unknown etiology, its primary therapeutic goal is to treat and maintain clinical remission (Sinopoulou et al, 2021). In addition to diet control, the existing standard treatment mainly includes the use of aminosalicylic acids, glucocorticoids, immunosuppressors, and biologics (De Maio et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

Potential of natural flavonols and flavanones in the treatment of ulcerative colitis

Tang²,

Ye³

et al. 2023

Front. Pharmacol.

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Ulcerative colitis (UC) is an inflammatory bowel disease generally characterized by chronic, persistent, recurrent, and non-specific ulcers of the intestine. Its main clinical manifestations include abdominal pain, diarrhea, and bloody stools. This disease is difficult to cure and even carries the risk of canceration. It has been listed as a modern refractory disease by the World Health Organization. Though a large amount of drugs are available for the inhibition of UC, the conventional treatment such as aminosalicylic acids, glucocorticoids, immunosuppressors, and biological agents possess certain limitations and serious side effects. Therefore, it is urgently needed for safe and effective drugs of UC, and natural-derived flavonols and flavanones showed tremendous potential. The present study concentrated on the progress of natural-derived flavonols and flavanones from edible and pharmaceutical plants for the remedy of UC over the last two decades. The potential pharmaceutical of natural-derived flavonols and flavanones against UC were closely connected with the modulation of gut microflora, gut barrier function, inflammatory reactions, oxidative stress, and apoptosis. The excellent efficacy and safety of natural flavonols and flavanones make them prospective drug candidates for UC suppression.

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Interventions for the management of abdominal pain in ulcerative colitis

Abstract: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To assess the e icacy and safety of interventions for managing abdominal pain in ulcerative colitis.

Cited by 12 publications

References 61 publications

Comparison and recommendation of dietary patterns based on nutrients for Eastern and Western patients with inflammatory bowel disease

Comparison and recommendation of dietary patterns based on nutrients for Eastern and Western patients with inflammatory bowel disease

Microbiota-Immune Interactions in Ulcerative Colitis and Colitis Associated Cancer and Emerging Microbiota-Based Therapies

Potential of natural flavonols and flavanones in the treatment of ulcerative colitis

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