Mild Oxidation of Oxime Derivatives with KMnO<sub>4</sub> in Ionic Liquid Media

Safaei‐Ghomi, Javad; Hajipour, Abdol R.

doi:10.1002/jccs.200900061

Cited by 10 publications

(5 citation statements)

References 36 publications

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“…[36][37][38] In the continuation of ongoing studies on the application of IL media, it was found that dialkylimidazolium halide derivatives have many advantages over conventional solvents. [39][40][41][42] These reagents are safe, easy to handle, environmenttally benign and present fewer disposal problems. Therefore, butylmethylimidazolium bromide ([bmim]Br) (Scheme 1) could be an excellent candidate for employment in organic reactions.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media

Safaei‐Ghomi

Ghasemzadeh

2012

JSCS

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Biologically active isoxazoline derivatives were efficiently synthesized in excellent yields and in less reaction time using mild, effective and environmentally friendly butylmethylimidazolium bromide as solvent and catalyst. By use of this catalyst isoxazoline derivatives are produced via cyclization reaction of chalcone and hydroxylamine hydrochloride in ionic liquids media. The separation of the product was facile and the catalyst could be separated and recycled. Our method is very quick, safe and avoids the use of hazardous and expensive reagents and solvents

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Section: Introductionmentioning

confidence: 99%

Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media

Safaei‐Ghomi

Ghasemzadeh

2012

JSCS

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“…This cyclization reaction of hydroxylamine and chalcone provided isoxazoline derivatives in the ionic liquid butylmethylimidazolium bromide as a catalyst (Scheme 29). [71] Results displayed that IL media, i. e., dialkylimidazolium halide derivatives, have several advantages in comparison to the traditional solvents [67–70] . So [bmim]Br was found to be an excellent catalyst to be used in organic synthesis because it enhances higher selectivity, reaction rates, cleaner products, and simplicity in contrast to the traditional procedures.…”

Section: Five‐membered Heterocycle Having Nitrogen and Oxygen Atomsmentioning

confidence: 99%

Recent advances in the synthesis of five‐ and six‐membered heterocycles as bioactive skeleton: A concise overview

et al. 2022

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Heterocyclic compounds play a tremendous role in the field of medicinal chemistry due to their association with diverse pharmacological properties. Most of the pharmaceutical drugs used in medicines possess a wide range of heterocyclic nucleus. It was decided basis on literature studies that various synthetic protocols like microwave‐assisted, nanocatalysed, green synthesis, click reaction, and multicomponent routes could be used for the betterment of the purity of products, selectivity, and better yields of the products. We have focused attention on the development of synthetic strategies of the above‐mentioned moieties because N‐, O‐ and S‐ containing heterocyclic compounds have seemed owing to a wide diversity of their biological activities viz. antioxidant, anticancer, anticonvulsant, anti‐inflammatory, neuroprotective, antiproliferative, anti‐obesity, antihyperglycemic, antihypercholesteroler, antiulcer, antidiabetic, antileishmanial, antitrypanosomal, antibiotic, etc. In this review article, an overview of the applications of synthetic protocols for the preparation of five‐membered and six‐membered heterocyclic compounds containing two or more heteroatoms (O, N, S) at different‐different positions along with their different potent and competent candidates against various diseases is presented in last 10–15 years.

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“…Safaei-Ghomi and Hajipour 281 investigated the oxidative cleavage of some oximes with KMnO 4 as oxidant in the presence of [BMIM][Br] under solvent-free conditions. Yields above 81% could be obtained with an oxime:IL:KMnO 4 ratio of 1:0.7:1.4 at room temperature without any further oxidation of aldehydes to acids.…”

Section: Oxidation Of Oximesmentioning

confidence: 99%

Ionic Liquids in Selective Oxidation: Catalysts and Solvents

et al. 2017

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Selective oxidation has an important role in environmental and green chemistry (e.g., oxidative desulfurization of fuels and oxidative removal of mercury) as well as chemicals and intermediates chemistry to obtain high-value-added special products (e.g., organic sulfoxides and sulfones, aldehydes, ketones, carboxylic acids, epoxides, esters, and lactones). Due to their unique physical properties such as the nonvolatility, thermal stability, nonexplosion, high polarity, and temperature-dependent miscibility with water, ionic liquids (ILs) have attracted considerable attention as reaction solvents and media for selective oxidations and are considered as green alternatives to volatile organic solvents. Moreover, for easy separation and recyclable utilization, IL catalysts have attracted unprecedented attention as "biphasic catalyst" or "immobilized catalyst" by immobilizing metal- or nonmetal-containing ILs onto mineral or polymer supports to combine the unique properties of ILs (chemical and thermal stability, capacity for extraction of polar substrates and reaction products) with the extended surface of the supports. This review highlights the most recent outcomes on ILs in several important typical oxidation reactions. The contents are arranged in the series of oxidation of sulfides, oxidation of alcohols, epoxidation of alkenes, Baeyer-Villiger oxidation reaction, oxidation of alkanes, and oxidation of other compounds step by step involving ILs as solvents, catalysts, reagents, or their combinations.

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Mild Oxidation of Oxime Derivatives with KMnO₄ in Ionic Liquid Media

Cited by 10 publications

References 36 publications

Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media

Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media

Recent advances in the synthesis of five‐ and six‐membered heterocycles as bioactive skeleton: A concise overview

Ionic Liquids in Selective Oxidation: Catalysts and Solvents

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Mild Oxidation of Oxime Derivatives with KMnO4 in Ionic Liquid Media

Cited by 10 publications

References 36 publications

Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media

Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media

Recent advances in the synthesis of five‐ and six‐membered heterocycles as bioactive skeleton: A concise overview

Ionic Liquids in Selective Oxidation: Catalysts and Solvents

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Product

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Mild Oxidation of Oxime Derivatives with KMnO₄ in Ionic Liquid Media