Mikrobielle Besiedlung der Hände und ihre epidemiologische Bedeutung

Kampf, Günter

doi:10.1007/978-3-642-55718-7_2

Cited by 4 publications

(2 citation statements)

References 128 publications

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“…From the inanimate environment, nosocomial pathogens can be transmitted to hands quite easily. 9 SARS-CoV has been described to persist on surfaces for up to 96 h. 10 In another study, dried SARS-CoV retained its infectivity for as long as six days, indicating a relatively strong survival ability. Only after nine days in a dried state did SARS-CoV completely lose its infectivity.…”

Section: Introductionmentioning

confidence: 96%

Efficacy of various disinfectants against SARS coronavirus

Rabenau

Kampf

Cinatl

et al. 2005

Journal of Hospital Infection

Self Cite

261

248

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The recent severe acute respiratory syndrome (SARS) epidemic in Asia and Northern America led to broad use of various types of disinfectant in order to control the public spread of the highly contagious virus. However, only limited data were available to demonstrate their efficacy against SARS coronavirus (SARS-CoV). We therefore investigated eight disinfectants for their activity against SARS-CoV according to prEN 14476. Four hand rubs were tested at 30s (Sterillium, based on 45% iso-propanol, 30% n-propanol and 0.2% mecetronium etilsulphate; Sterillium Rub, based on 80% ethanol; Sterillium Gel, based on 85% ethanol; Sterillium Virugard, based on 95% ethanol). Three surface disinfectants were investigated at 0.5% for 30 min and 60 min (Mikrobac forte, based on benzalkonium chloride and laurylamine; Kohrsolin FF, based on benzalkonium chloride, glutaraldehyde and didecyldimonium chloride; Dismozon pur, based on magnesium monoperphthalate), and one instrument disinfectant was investigated at 4% for 15 min, 3% for 30 min and 2% for 60 min [Korsolex basic, based on glutaraldehyde and (ethylenedioxy)dimethanol]. Three types of organic load were used: 0.3% albumin, 10% fetal calf serum, and 0.3% albumin with 0.3% sheep erythrocytes. Virus titres were determined by a quantitative test (endpoint titration) in 96-well microtitre plates. With all tested preparations, SARS-CoV was inactivated to below the limit of detection (reduction factor mostly > or =4), regardless of the type of organic load. In summary, SARS-CoV can be inactivated quite easily with many commonly used disinfectants.

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Section: Introductionmentioning

confidence: 96%

Efficacy of various disinfectants against SARS coronavirus

Rabenau

Kampf

Cinatl

et al. 2005

Journal of Hospital Infection

Self Cite

261

248

View full text Add to dashboard Cite

show abstract

“…14 The resistance of FCV to various chemical agents is considered to be high. 15 Although colonization of healthcare workers' hands with viruses is less common than with bacteria, 16,17 it has nevertheless been suggested as a key measure in the spread of norovirus in hospitals. 18 The recent Centers for Disease Control and Prevention guideline suggests the use of alcohol-based hand rubs in hospitals if hands are not visibly soiled.…”

Section: Introductionmentioning

confidence: 99%